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Gene information for ATP6V0C (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID527
Official gene symbolATP6V0C
Full nameATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Aliases,ATP6C,ATP6L,ATPL,VATL,VPPC,Vma3,
Gene summaryThis gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq]
LocationChromosome: 16   Locus: 16p13.3
Gene position2563953 - 2570219  Map Viewer
Gene orientationplus
Gene size6267 bp
Gene sequence
OMIM ID108745