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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PKM (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5315
Official gene symbolPKM
Full namepyruvate kinase, muscle
Aliases,CTHBP,HEL-S-30,OIP3,PK3,PKM2,TCB,THBP1,
Gene summaryThis gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q22
Gene position72523684 - 72491370  Map Viewer
Gene orientationminus
Gene size32315 bp
Gene sequence
OMIM ID179050