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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PLA2G2A (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5320 Official gene symbol PLA2G2A Full name phospholipase A2, group IIA (platelets, synovial fluid) Aliases ,MOM1,PLA2,PLA2B,PLA2L,PLA2S,PLAS1,sPLA2, Gene summary The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene. Location Chromosome: 1   Locus: 1p35 Gene position 20306932 - 20301924  Map Viewer Gene orientation minus Gene size 5009 bp Gene sequence >PLA2G2A:complement(6982012..6987020):Length=5009 GAGTCAGTGTCAGCCCGAAGGCTGAAGGAAAAAGAGCAACAGATCCAGGGAGCATTCACC TGCCCTGTCTCCAAACAGGTGAGGATGGGGAATAAAGTGAAGGCAGTGCTTTGGTGGGAA CTTCAAGGATAGCCTCTGGCTTTTTCCAGGTTTAGAAGCTCATATGAGACAGGGGTGGAG GAAAAGAAGAAAGAAGAATAAGAAGAGAAAGTTGAGGCCCTGGCCCAAGTTAGTGGGAAG GGAAATCCACCCCCATTAAACTCTCTCCCTGGTGGACTGTGGGGTGCACACGTGAGGCCT GCACAGGTGCTGGAACATGGTAGAGGCCCAGGACATACTTCCTGTGAATGAATGATTGAG CGGCTGAATGAATGAGTACCACTAAAAGCCCTCTTTTCTATTCCCAAATGCCACATTGAG CAGAAGGGAGCAATCCTTGCTCAGCAATTGGTAGTCCCTTTGGGTGTGCAAATGAGTCCA CAGCCTGCAACAGCAGACAGTCTCTGCCCCCCTTAGAGGCGATTGCAGGGAGGTGGCTGA CCGTTGATCACACCCAGAGCTGGTTATGGGAATTTACTCCATGGAAAGACTGCAAAACTG CCTGAAATGTGTTTTGGCATCAGCTACTGACACGTAAGGTTTCCCAATCCTCAACTCTGT CCTGCCAGCTGATGAGGGGAAGGAAAGGGATTACCTAGGGGTATGGGCGACCAATCCTGA GTCCACCAACTGACCACGCCCATCCCCAGCCTTGTGCCTCACCTACCCCCAACCTCCCAG AGGGAGCAGCTATTTAAGGGGAGCAGGAGTGCAGAACAAACAAGACGGCCTGGGGATACA ACTCTGGAGTCCTCTGAGAGGTAAAGAGCCAGCGAAGCTGATGTCCTGTCAAGAGCAGAA TTCCTGCTCATTCGCTGCCTTTGAGAGTGGCTGTGTTGTGCATGCATGTGCATGATTTGA TATGTATGAGAGGGTGTGTGTGCATGAGTGTGTTGAGTGAGTATGTGAGTGTAGTGTAAG AGAGGATGTTGGCACTATCAGGTAAGTACGAGAGTGTGTGTATGTGGGCATAGGTGTGTT AACATGTATGTGTTTGGGAACTTGTGTATGTGGAAGGGGTTAGAAGGCCTAGAAGAGAGA GGTTGATGCTTTCATTCTGGAGGAAAATACTGAGGCCGAGCCTCCATGGGTGCCTTGGAG ACTCCAAGCCTTGAATCCAGTGTGGGGATATGCAAGCTATGTCTAGCGAGGGACACATCC TCTGACCTCAGGAACCTCCCAGGTAGTTGGGAGGAACCTGGTTCCAACCTCCCAAGAACT CTCAGTCTGATGAGGTACAGGGGAGGTCTCATTAGTGTATCATGGGGTTCTCCACAGGTC TGAGGGCCTGATGTGTGTGAAACCATTCTGCAGAGCTGGGAACGGGTCAGGAGGTGGTTG TGTGTGTGTGTGTGTGTGTGTGTGTGCATTGCTGGAGGGCACTCCTTGTGTGCTCTGAGT GTGACAGAGGAAGTCACCCTGGACTTAGGTTGGATGGGAGAGCATGTCTGTGTGTCTCAG AGCCACCAAGGAGGAGCAGGGGAGCGACGGCCGGGGCAGAAGTTGAGACCACCCAGCAGA GGAGCTAGGCCAGTCCATCTGCATTTGTCACCCAAGAACTCTTACCATGAAGACCCTCCT ACTGTTGGCAGTGATCATGATCTTTGGTAAGAGCTGACCCTGACCTCTGAGCATGGGGGG ACAGCCCCAGAAGGGAAGCACTCTTGTCCCTTAGTTTTCTCTCCCATTGCAGTGATCCTC TCTCAGGGGGAAAAAAGAAGCCATTTGGGAGGAAGGAGAGTAGCAGAGAGGGGCAGAGAG GGAGGGCGCAGAACCCCATGCCCCATCACCAGACAACTCCCAAATTTCCTTCCAGGCCTA CTGCAGGCCCATGGGAATTTGGTGAATTTCCACAGAATGATCAAGTTGACGACAGGAAAG GAAGCCGCACTCAGTTATGGCTTCTACGGCTGCCACTGTGGCGTGGGTGGCAGAGGATCC CCCAAGGATGCAACGGATCGGTGAGGCCACCTATCCCTCCCTACCCTCCTAGACTCTGGC CCAGGCAGGGCTGGGAGCTGCAAAGACAGTGCCGGTTCCTGATGGGCGCAGAGGTCTCAG GATGGCCTGGCTGGAAAAGCAGCCGGCATGTTGGAACTTCTGCTCTAGACTGTTGCAAAG TCACTGGGTCTCTGCCCAGGGTCCAAGGGGGTGAGACCACAGGCACCAGGCCTCCTGGAG CTGTGGGACAAGAGCCCCAACAGGGTGTCTCCTCACAGCTGCTGTGTCACTCATGACTGT TGCTACAAACGTCTGGAGAAACGTGGATGTGGCACCAAATTTCTGAGCTACAAGTTTAGC AACTCGGGGAGCAGAATCACCTGTGGTAAGAGTCCTACCTCACCATCGAGTGGCCCTCAT TTGTTTAGACAGTGCTGGGGACTGTGCTGGGCACCAAAGATAGACACAGAGGGACACAGT TCCTGCTTCAGGAAGCTCACGGTTGAGTGGGAAGCCAGGAAAGTGAAAATCCAATGTAGT AAAGACTCCAGTGGGAAGTAAACAAACAGATAAGGCATTAACACAGCCTGAGGCTTGAGG AAGGCTCCTGGAAGGGGTGACCCCTAAGCTGAGTCTGAAAGGCTGTGCAGAGAGTCAGGG AAGAGGAGGGAGCATTCCCAGAAGAGGACACAGCATGGTCAAAGGCACTAAAGGGCACTG TAAGCCATTCTGTACTGCCCAGCAGAAACATGAGGAAGAGGAGCAGTGCTGAGCCATGAT GCTGGAGACATAGGAAGGAGCTAGGTCAATCCGGCCCTCCAGGCCGGGCTGTATTTAGGT TTTGCCCTAAAGCAATAGGATGCTATTAAGCAAAGGAGCTACAGGGTCAGATTTGCATTT TAGATGACTCACTGTGGGGACAGGGTCGATGGAGACAAGTGGAAGGGGGGCAGAGAAAGC TATTGCCATCATGCAGGCAAGAGGGAGTAACATCTTGACATAAAACAATGGAGGTCAGGA TGGGAAAGGTGGAGAAAAAATCAAGATGCATTTGAGATGGAATCAGCTGAACTGGTGACT GAGTTGGGAGGGATGGGGAGAGGGAGTTGTTGGATGGATATGTGGCTGCATGGATGGCAC AACTGTGATAAAGACCATGGGAGCAGGTCATGGTGGAGGGTGGGGAGGAGCAGTTCTATT TCCAGCATGTTGAGTTTAGGGGCCTCCAGCACCCAGGGAGGGGTCCAGCAGGCAGCTGTC TATACAAATGCAGCTCAGGGGAGAATTCAGGACTGGGACACAGATTCAGAAGCCAGCAGC AGAGACCTGAGAGGTGGGTGTGATCACTCATTTGCTGTTTAAAGGCCCAGAAAGGAGACA GAGAAGGGATGGACAGAGAGGGAGAAGGGGAACTGAGCGAGAAGGTCAAGGAGTCAGTAA GGAAATGGTTAGCAAGGGCCAAGTGAACAGGGAGTCCTCCATGAAAAGGGCCAACAAGGC TCCCCTGGATGTTGAGGCAGAAACGCATGAGGGACTCAGGGGAAGCTGTTTCCATGGAGT CGGGAGGGCAAAGCCAGATTAGACCAGGTGGGGGCTGATGGGAAGGCAAATAAAGACAGG AGGCAAAGACAACATTCTGGAGAAAGTTTGGCCCTGAAGGGGAGGAGAGGTGGGTGGCAC TGGAAGGCTTTGCTTGGTGTCCCCAGACAGCTGACTCATGAGTGGGATTTGGAAAAAGCG TGGACTCCTGCCCATGGCCTGAGTCCTTTAAGATCAGAAATTATGTCTCCCATCATGGCC TCTCCATAGAGGCATGTATCTTCAGCAGGCGTTAGGTCACAAGCCACATGATGCCAAGCT GACAGTGGCTTGCATAATGGGGATATGTGACTGTCGCATAACTAGAATTCTGGAAGAGTG CAGTGCCAGGCTTGGGGCAGCTTTCCAGCCATGTCATTAAGAATCCAGCCTTCTCCTGGC CTTCAGCTATGCCACGTGGCCAGTGTCTACACCTGGGATGTCAAGAGACAGGCTGCAGGT CCACCCTCCTGGCCTCATACTATGGAAGAGGCTTTCCTTTTGGGCATCTCTCTTTTTGGA GGGAGGAAATAGATCGTTCCCAGAAGCCCCCAGCAGACTTCCCCTTGTTGCTCATTGGTT GGAACAAGGTTACATGATACACAAAGACCAATCACTGCAAAGGAAAAAGGGATGACCCTG CCTGGCTTACACCAATCACAATCTATTCCCAGACCCCCGAGGCTAGGGCTTTGCCTCCTG GACACATCTGTTAGCAAGAGGAAGAGATTATGGCTGTTAGGAAGGCCTTTGAGAAAGTAT CCCAGTGCCTGGCTGTGTCTCCACCAGGCTGGAGGCCAGCATCCCAAGGGCAAGAATTCT GTCTCCCCATTGGTCAGAAATATCTGGAGCGCAGGTGTTTGTCTCCAACTAGGAGCTTCT GGAGGACAGGGCTGTGTCTTCTACCCCAGGGTTCCCACAAGAAGCCACTGAATATTAATA AACTCCCATCTTGTGTTTATTTTCTTATGATTTCAGCAAAACAGGACTCCTGCAGAAGTC AACTGTGTGAGTGTGATAAGGCTGCTGCCACCTGTTTTGCTAGAAACAAGACGACCTACA ATAAAAAGTACCAGTACTATTCCAATAAACACTGCAGAGGGAGCACCCCTCGTTGCTGAG TCCCCTCTTCCCTGGAAACCTTCCACCCAGTGCTGAATTTCCCTCTCTCATACCCTCCCT CCCTACCCTAACCAAGTTCCTTGGCCATGCAGAAAGCATCCCTCACCCATCCTAGAGGCC AGGCAGGAGCCCTTCTATACCCACCCAGAATGAGACATCCAGCAGATTTCCAGCCTTCTA CTGCTCTCCTCCACCTCAACTCCGTGCTTAACCAAAGAAGCTGTACTCCGGGGGGTCTCT TCTGAATAAAGCAATTAGCAAATCATGTA OMIM ID 172411