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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ATP6V1G2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 534 Official gene symbol ATP6V1G2 Full name ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 Aliases ,ATP6G,ATP6G2,NG38,VMA10, Gene summary This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] Location Chromosome: 6   Locus: 6p21.3 Gene position 31514627 - 31512239  Map Viewer Gene orientation minus Gene size 2389 bp Gene sequence >ATP6V1G2:complement(3021898..3024282):Length=2385 GGCTAACCTGTTGTAAGCCCGCAGCTTTGGGCCTGGTCTCTGCTGCTCCCAGGCGGCCCC TTTGGGTACTGCCTGAGCAAGAAGTGCTGGAGAGGAGGACCAGTCATCAATAGGAGGATG AGATTGGGAGAGACACTCGGTGCAGGAGGCTGAGTGAGCAGGGGAGCACTAAGACCCAGG GGTAGTGGAGGACTGCAGCAACGAGCTGGAGGAGGAGAAGTAAGCGGTGGGGGGTGGGAG CCATCTGGTACTTTGACAGCATTCAAAACAGCATCGGCCATAACAACAGAAATGGCCAGT CAGTCCCAAGGTATCCAGCAGCTTCTGCAAGCTGAGAAGCGGGCAGCTGAGAAGGTGGCA GATGCCAGAAAGAGTGAGTCCCCTCTTTCCTCCCTTAGGAGTTTGGAAAGAAAATTGGGG GTGGGGGACAGCAAACATTTTGGGAAAACCCAAGGCTGGCGGGAAGACAGCTAGGGTCTG GAGGCTGGTTAGGAGGGAAGAAATGGATGGATATTAGAATCTGGCACCTGGTTGGCTGAG AGAAGGCTGTATAACTTTCTGGAAGGGACTGACTCCTGCTATTACATTGTGTGTGTGTGG GTCCATCCCCACTCACTGTCCTTTCTTCTGCCTCCAGGGAAGGCCCGGCGACTGAAGCAG GCAAAGGAGGAGGCACAGATGGAGGTGGAGCAATACCGCAGAGAGCGAGAGCACGAATTC CAGAGCAAGCAGCAGGCGGTGAGTTGAGGCAGAGTCGGGATGAGACCCCACTGCAAGTTG GTGGGTGCATCTAGTGAGGTGTGTAAGGGTGACTCAACAAGAAAATATGGTGGCAGAGGG CTGAGGCTGAGGGGACCCTGGCAGGGACCACAACATTGGTGAAACTTTGTGATGATATGT AGGAGAGTCTGGGAGTTTTGAAGGCCACATAGAGCTTGTGGGCGGAATGCCACAGTCTGT GTAAAGTATAACATCTATGTGGAGTATGATTAACATTTGTGGTGGAGGGTAGAGTTTTAT GGTCATGGATGGTGAGGTGGTGGGGATATTACGGTCTGTTTTAGGATGAAGTTGCATGTT AGGTCTAAGGGGAAAGGGGACTGTGTTGATCTCTTTGGTGTTGGGATATTTCTGTGGGAT GGGGGTGGTTTCTGAGAGGGCCTTTCTTCTAGGCTTTGTTTCAGGATCTTTCCCCTCATA TGCCTGGACCCTTGTCTGTTTCTGCTTTTCCCTTTCTCTCTTCCACCCCTCTCCCTACCC CCCAGGCCATGGGCTCCCAGGGGAACCTGTCTGCTGAGGTGGAGCAGGCTACAAGGCGCC AGGTGCAGGGCATGCAGAGCTCCCAGCAGAGAAACCGAGAGCGTGTCCTGGCCCAGCTTC TTGGCATGGTCTGCGACGTCAGGCCCCAGGTCCACCCCAACTACCGGATTTCTGCCTAGG GCCACCGTAGGGCCTGACTCCTTCTGCCAGTTCCCTCCCTCAAAGAAATCCTCCAATCAA AATCACCTCCCACCATAATCCCTGTCTTCTTTCCATCCCCTAGAAATCCTGGGAGGCAGG ATCCAATAATTTTCCTGTGACACTTATAAATATCCTGCTCACATCTGAATCTCCTTGTTG TTCTTTAACCCTCACTGGGACTTTGTAAACTTCCAAGTCATTCTCACCTAAACCCTCTGT GAAATTTGTAATATGGGGAAGTAGGAATGTGGAAAACATCCTGACTTCAGTGTCTGGCCG ATGTGGGTCCCTCTCTTGACCCTGTCACTTGCTGGCTGTGAAACCAGGACAAGCTACTTA ACTTGGTAGCCTCGATGTCCTCCTCTGTGAAACTGGGATGATAATAATGCCTACCTTGTG AGGGTTGCTTCAATGATTAGGAATCATTCTGTAAAGTCTAGCAGAGTTCCTTGCATGTTG TAGCAGTGATTCAGTAAGTAGCAACCCTGTGATACTATTACCACCACCTGCTCACTGGTC AAAACCTACACAGCTGTTTCCTCACGTCCATCACTGGCTCTCTAATTCCACTTGTTCATT CTGTGACCCTAGTTATTTTCTGAAAAATTGGTTCTTCTCTTTTCCCAGAGACCTTCTGAT CTCCAAAAAGAGGAGATGACTACATTTAGCCCCTCTCTTATAATTCCAGGTAGATAACTG CATTTTGTAGCCTCTCTTTGTTTTTCTTTTGCTGATCTTTGTCTTTATTAGATTTTCCTC CTTTCCTATTTCCCCAAAGACTTATCAGATGCTCATTGCTTTCTAAGATCTAAAATGATA CTGTGTTCCCTCATATGCATGCCCTTCCTTTCTATATCCTTGACACCTTACTTTCCCATT GTAACAATAAAAAAAGTATCAATAAAATAATTATTGGCAAATAAA OMIM ID 606853