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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PLG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5340
Official gene symbolPLG
Full nameplasminogen
Aliases,DKFZp779M0222,
Gene summaryThe protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
LocationChromosome: 6   Locus: 6q26
Gene position161123225 - 161175086  Map Viewer
Gene orientationplus
Gene size51862 bp
Gene sequence
OMIM ID173350