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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MBD3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID53615
Official gene symbolMBD3
Full namemethyl-CpG binding domain protein 3
Aliases,-,
Gene summaryDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.3
Gene position1592652 - 1576678  Map Viewer
Gene orientationminus
Gene size15975 bp
Gene sequence