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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PRKAG3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 53632 Official gene symbol PRKAG3 Full name protein kinase, AMP-activated, gamma 3 non-catalytic subunit Aliases ,AMPKG3, Gene summary The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq] Location Chromosome: 2   Locus: 2q35 Gene position 219696512 - 219687106  Map Viewer Gene orientation minus Gene size 9407 bp Gene sequence >PRKAG3:complement(69896524..69905930):Length=9407 TTGGTCTGGGGCTGGCCACATGGAGCCCGGGCTGGAGCACGCACTGCGCAGGGTATGGGG GTCCCAGGGGAGCCGGAGCCGGGGCAGCTGAGGCCAGAAGATTGAGCGCACGGGCTGTGA ATGTGTGTGTGGGCGTGTGTGTCTTCTGGTGTGTGTTTGGTCTGGATTTTCTCGTGAATA TGGGCATGTGCATGTTTGGGCATATGTATTGTGAGTGTGTGTGGTTCTGTGTGCCTGGGA GTGTTTGGATGTGTGTGTTTCTGTGTGTGTTTGTGTATGGCTGCATGTCTGTGTATGGCG TGTGTCTGAGCGTGTGTATTGGTGTGCATGGGTGTGTAGGCGTGTGTTCAGGGAGAAGGG GTTTGGGAATGTAAGGCACTTTCCCCACTCCTTCAGAAACTCTTCTCCCCACAGACCCCT TCCTGGAGCAGCCTTGGGGGTTCTGAGCATCAAGGTAGGGAGAATGCCCCCTCCCTGGGG CCTAACCTCTTCCCCCACCTCCTTGTCCCCCACTTTTCTGGGACCCCAATTCCCTCCCAG CCTGGCTTTTATCTTCCTCCTTTTGGTCTTTCTTCCTCATTGTTCTTCCTCCTTTCCCCA GGTGTGTTTCCCTCACCTCCAATTTCCTCTTTTCAGAAGTGACTTTCCCACTTACTTGCT GTGTGATTTGCAGCAAATTGCTTAACCTCTCTGAATTTCTGGTCCCTCACTAGCAAAATA GGGATGATAATAATGCCTGCTTTATAAGGCTGCTGTAAGTTTTAAATGAGAAATATGTTG GAGAAAAGCCCATTGGAAGCTTGCAAATCCTAAAGATTATGAATAACATTTGAATTGATT TTGATGCATTACTCCCTATTAACCAAACAGGCCCCATTCCCCTTCCAGAGATGAGCTTCC TAGAGCAAGAAAACAGCAGCTCATGGCCATCACCAGCTGTGACCAGCAGCTCAGAAAGAA TCCGTGGGAAACGGAGGGCCAAAGCCTTGAGATGGACAAGGCAGAAGTCGGTGGAGGAAG GGGAGCCACCAGGTCAGGGGGAAGGTGAGGCCAAGGCCAGTTCTGGGGAGGTGGGAGCCA GGGGAGTGGGAAATCCCAGAGGAGCCTGGGTCTGGTCTCTACCTCAGGTCCCTCCATAAC ACAGAGTTGGACCCAACCTTCATCTTGTGGCCTCAGTCTCCCTACATAGTAGAGAACAAG GCACTGCAGTGCCAGAGGCCAGCATGGCCAACTCAGAAAGATGGGACAGAGCCACTACCT GGGGCGACTCTCAGGTCAGCCCCTCACCTGCAAATAGGGCCACAGCATCCAGGCTTCCCA CTGCTGCTGTGAGATGAATGGCGACAGCAGATGAGAACGTGCTTTGGAAGATGGAGTTAC TGTCCTCTTCCCCTCCTCCCCCAAACAGGTCCCCGGTCCAGGCCAGCTGCTGAGTCCACC GGGCTGGAGGCCACATTCCCCAAGACCACACCCTTGGCTCAAGCTGATCCTGCCGGGGTG GGCACTCCACCAACAGGGTGGGACTGCCTCCCCTCTGACTGTACAGCCTCAGCTGCAGGC TCCAGCACAGATGATGTGGAGCTGGCCACGGAGTTCCCAGCCACAGAGGCCTGGGAGTGT GAGCTAGAAGGCCTGCTGGAAGAGAGGCCTGCCCTGTGCCTGTCCCCGCAGGCCCCATTT CCCAAGCTGGGCTGGGATGACGAACTGCGGAAACCCGGCGCCCAGATCTACATGCGCTTC ATGCAGGAGCACACCTGCTACGATGCCATGGCAACTAGCTCCAAGCTAGTCATCTTCGAC ACCATGCTGGAGGTGAGGCCACGGCTCTGCCCAACCTGTACTCACTCTCCATCCACACGG TGCTGCAGCCGCCACTCCCACCCTGCAGGATGCCCTGCTGAGCCAGGTGCCCCTGCAAGC CCCCTGAAAGGACTCCTTCTTAGCACTATGGAGGCCAGTTGGGGGAGGGACAGCTTCTAC TCTCTGTTAGCACACGTAATTGTCATCACAGCTCTGCCACTTAGTAGCTGTAGGACCTTG AGTTACATTACCTTTCTTGTCTCTAAAATGGGGATCGAAATGCCTGCTGCACCCTACATA GTTCAGAGGATTCTTGGACTACCCAGTATAAAGCGTGAACAAAGTATGTGTAAGACATTG CAGAGGCCGGGCACGGTGGCTCATGTCTGTAATCCCAGCACTTTAGGAGGTCGAGGTGGG CAAATCACAAGGTCAGGAGTTCGAGACCGGCCTGACCAACATGGTGAAACCCCATCTCTA CTAAAAAAAAAAATACAAAAAATTAGCCGGCCGTGGTGGTGGGCGCCTGTAATCCCAGCT ACTTTGGAGGCTGAGGTAGGCGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCC GAGATCGTGCCACTGCACTCCAGCCCGGGAGACAGTGCGAAATTCCATGTCAAAAAAAAA AAAAGGCATCACAGAGTGACTTAGAAAAAAGAGTAGGGGACTCTCTTGGTAACAGAAAAA ATAATGAGCTCTGGCACCTGCTCTTCCATTAGGCTTAGCTATAAATGTCTATAATCTTAT TCTTATCATTGTTATGCAGTGCAGTGTTTCCCAAAACACGGTGTATGTATTGTCCATAGC ATGCATTTTGATTCTAATGGTTCGTGAAAAAATATGTCTATTTCAGTAGCTTTATATTTG TTTTAGGCTGTGTTAAAAAAATATAACCAGCATGTGCAGATAGTACTGCTTAGGACGGGG CACAAAATGAGTCAATATAAAATTTATCTACAAAAAAAGTATGTAAATATGCAAGTGTTA TGTAAATAACTATGCCTCCGGTACTTAGTCTATCAAAAACTAGACTGTGTCTGTACACAC ATACCCTCCAAATGGAAACATGAACTTAGAATTTCTCACTCCCTGGTGTGCCAGGTGAGG GGCTCATGGTCTCAGGCCACAGCCTTATCTATGTACATGTCCCCAGCAACGATCATGTCT AGCGTGTACTGTGACATGAGGAAGACAGGCCAGCTGGTGTAGAGGAGGGTCCAGGAGAAG GCCCCATGGAAGAACCCTGGGTGGGACAGGGAGGGGACAGCAGGCAGATGGGAGGTGCGC ACTGAGGGGCAGAGAGGGGGGTGAGGGTCTCTCGGGACCCACCCTTGACTGTTCTCCCTG GCCCCTCAGATCAAGAAGGCCTTCTTTGCTCTGGTGGCCAACGGTGTGCGGGCAGCCCCT CTATGGGACAGCAAGAAGCAGAGCTTTGTGGGTGAGGAGAGGCTGGGGAGGTGAAGGGAG ATGGAGGAGGTGAGGGGGAGATCTTGTACGGTTGTTCTGGGGCTGATCTCTGATATACCA CAAGCTTGGCTTCAGGCCAAGCCCAGCCAGGGGCCAGGGTGGAGGAAAGTCCATCCGGAG TCTGCATGGCCAGCTGGGAGACCCTGGGGCTCAATTTCCCCATCTGTGGAGCCGCTATGA CCAGCTGACACCTTTCACCTCCGCTACTGCATGGCCCTGTGCCATAGGTGCTAGGGAGCA AATGGGGGGAGGCAGGAGAGAAAGAGCCCCACTTCTCAGGCCTGGGGGGCTGCCCCACTG TCCTGTTCCCACAGTCCCCACTGTGTCTCAGCACAAGGACACTGGCAGGGTGGGGAGGGG ATCTGACCCTCAACCTGCCTTCCACCCAAAGGCCCCGGGCTGACCTCCTCCCCGCCCCTC CCTGCAGGGATGCTGACCATCACTGACTTCATCCTGGTGCTGCATCGCTACTACAGGTCC CCCCTGGTGAGGAGTGGGCTGGGAATCTTATGGGCACCCAGAGGGGCGGGGGCGGAGGGG AGTCCTCCTGGAGCCTGGTGCCCTAGAAGCCCACGTCTTTCTGACTTCTGGAGTCCTGTC GATGTCTCTAGGTCCAGATCTATGAGATTGAACAACATAAGATTGAGACCTGGAGGGGTG AGTGGGGAGAGGAACCCGGAAAGGGCTGTTGGTGATGGTGGGCCAGGGCTTAAGGTGGAG GATGGGCAGTGGGGATGTCCTGGAGTGAACAGGGGAGGGACAATAGGAGCCTCGGGTGCC TGACGGAAGGGAAGCTGCCTGGGACTGCAAGGTGAGGCAGGTGACCGGCTCCCCTGGCCT GACTCTGGCTCTTTCTGCAGAGATCTACCTGCAAGGCTGCTTCAAGCCTCTGGTCTCCAT CTCTCCTAATGATAGGTGGGTGTCTCTGCTCATTCACCTGAGCCTCCTCCTCCCACAGTC CCCTTCCCCAGTCCCACTCAGCTCTGAACTCACCTCTTCATCCTAGGCGGCACACAGACA AGGGAGCCTTGGTGCCCTGCCCTCCTTTTTAGGGGCCTGGGATGGAGGTTGTCTCTCCCT AGGCTGCCCCGAGGCTCACTGCTCCCATCTCTGCAGCCTGTTTGAAGCTGTCTACACCCT CATCAAGAACCGGATCCATCGCCTGCCTGTTCTTGACCCGGTGTCAGGCAACGTACTCCA CATCCTCACACACAAACGCCTGCTCAAGTTCCTGCACATCTTTGTAAGCCTGGGCCCAGG TGGGAGGAAGGGGGAGACCTGGGCAGGTGATCAGAGGGCCTGAGGAGTCTTCAGCCCTAG CAGTCGTGGGGAAGAGCTGGGAGCCCTCTTGAAGCTGCTGGATCCCTGATCTCCACCTGG TCCCCATCCTAACCAGGGTTCCCTGCTGCCCCGGCCCTCCTTCCTCTACCGCACTATCCA AGATTTGGGCATCGGCACATTCCGAGACTTGGCTGTGGTGCTGGAGACAGCACCCATCCT GACTGCACTGGACATCTTTGTGGACCGGCGTGTGTCTGCACTGCCTGTGGTCAACGAATG TGGTACCCACCCCCAGGATGAGAGGCTCGGGCTGGGCTGGGGCCTGGGAGAACCTGGTGG GGAGAATATGGGAAGGGCAGGGTTTCTCATGCCATCCCTGTGGGGGGTACAGGATGGACT GGGGATTAGAAGTCTCCGTCTACTCTGAGACTTGGGCAAGTTGCTTAGCCTCTCTGTGCC TCAGTTTCCTCCTTTGTGAAATGGGATTCTTCACAACACTCATCTTTCTGACTTCACAGG AGGATTTAAAAGGTTATGTGCATGAAAATGGGCATAGCGAGAGGAAGCAGCAGATTTTAG TTTCAGTTCATCTTAAAATGGAGCCGGACACGTGGTGCATGGCTGTAATGCCAGCCCTTT GAGAGAGGCCAGAGCGAGAAGGTCGCTTGAGGCCAGGAGTTTGAGTTTACATACAGTGAC ACTCCAACCTGGGCAACAGAGCAAGACCCTGTCTCTAAAATAATAATAACGAAATAATAA AATTTAAAAAATTAAATGTGCCATGGGACCTCGGGCCCCCAGCCAGCCCTCAATTTCCTA CACTGAAAAAGGGCTGCAGAAATGACAAGATTATTTCTTTGGTTGAATGATGGCTATGAA ATATTTCAAAGCTAAAATCACCATAATTAAGATAGATATCAAGAAGTGTTTTCAATTTAT TTTTGATTATAAAAAACTTCAAATGTATAGAAATGGTAGAAAGAAATTGCATAATGAACC ACCTATATCCATTGCCTAGATTAACTACTGTTACTATATTGCCATAACCAGTTCATCTTT TTCTCTGAAGTAATTCAAAGTAAATTACAGACATCATGTCATTTCACCCCTAAACACTTT AGTCTGCACTTCTTAAAACAAGTGTATTTTTGGCCAGGGGCGGTGGCTCATGCCTGTAAT CCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACGAGGTCAAGAGATCGAGACTATCCT GGCCAATATGATGAAACCCCATCTCTACTAAAACTACAAAAAAAAATTAGCTGGGCATGG TGGCGCACACCTCTAGTCCCAGCTACTTAGGAGGCTGAGGTAGGAGAATCGGTTGAACCT GGGAGGCAGAGGTTGCAGTGAGCCAAGATCGCGCCACTGTACTCCAGCCTGGCAACAGAG CGAGACTCCAAAAAAAAAAAAAAAAAGTGCATTTTATACCACCAAACAAAACCATGAATA ATTCATATTATTGTCTGACATCCAATCCTTATTCTCACTTCTCCATTTCCTCAAGAATGT TGGGTATTTTGGGTGTTGTTTTGGGATGGAGTCTCCCTCTGTCACTCAGGCTAAAGTGCA GTGGTGCCATCTCGGCTCACTGCAACCTCTGCCTCCCGAGTTCAAGTGATTCTTGTGCCT CAGCCTCCTGAGTAGCTGGGATTACAGGCAAATGACACCACGCCCAGCTAATTTTTGGGG GGTATTTTTAGTAGAGATGAGGTTTCACCATATAGGCCAGGCCAGTCTCCAACTCCTGAC CTCAAGTGATCCACCTGTCTTGGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACCG CGACCGGCCAAGAATTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCGCCTG GGCTAGAATGCAATGGTGCAATCTTGGCTCACTGCAACCTCCACCTCCCAGATTCAAGCA ATTCTCCTGCCTCAGCCGCCCAAATAGCTGGGTTTACAGGTGCGTGCCATCACACCTGGC TAATTTTTTGTATCTTTAGTAGAGATGGGGTTTCACTATGTTGGCCAGGCTGGTTTTGAA CTCCTGACCTTGTGATCCACCCACCTCGGCCTCCCAAGGGAATGTATTTTTCATAGTTGA TGTGTTCAAAACAGGATCCAATTGAAGTCCATGGTTTACATTCGTGTCTTTTGTTCCTTA AATCTCTTTAAATCTATAACAGCTCCATTCCCCCTAAATTGTTATGACGTGGGTGAGTTG AAAAGCCTGGGTCAGTTGTCCTATAGGATACCCCACATCCAGATTTGTCTGTTTGCTTTC TAGAGCTGGCCTTTACTTTGTTCTCTATTCCTGGGTTTCCTGTAAACTGAAATTATATCT AAAGGCTTGAAGAGATTTGGGCAATAAATTCGAGGCTAGACTATTTTGTAGGTGGTGCCA TGTTACTCACACTGCATTTCCTCAGGATGCTCAATGTCAGGCTGTCTCACTCTGGGATGC TAAGTTTGATCCTTGGGTTCTGGTAGTGGCACCCTGATGCAAATAGCCCTAGGCCCTCTA CACAGCACCCCGGTTCTGACCGGAGCCTCTTCCCTGTCTTTCTCCCCCCACCCCCCACAA CCACCCTCTGCAGGTCAGGTCGTGGGCCTCTATTCCCGCTTTGATGTGATTGTAAGTGTC GCTGGAAAGGTGGGATGCTGCAGGGAGGCTAAGGGTGTGGGGATGGGTGGGGGGCCTCTG TGGACCAGGGGGACCTTGACAAGTATGCAGGGGTTGACATCTGTAGGGTAGGAGCCCAGG CAAGGGGGTGACTAGGAGCCATACTTCTCTCTCTGCCCCAGCACCTGGCTGCCCAGCAAA CCTACAACCACCTGGACATGAGTGTGGGAGAAGCCCTGAGGCAGAGGACACTATGTCTGG AGGGAGTCCTTTCCTGCCAGCCCCACGAGAGCTTGGGGGAAGTGATCGACAGGATTGCTC GGGAGCAGGTACCGTGTGCCCTCCATTCATGCCCCCAACACATATAGCCCAGTCCTTCTC ATGCACGGCTCCAGCCATCCCTGAACATCGGGCACCTGGCCTATCCTTCCATTTCATGAC CAACTCCTGGTGCCCACACTGGCCTGCACCTGGTCCTGTCCATGGGGCCCTTATGCCAGG GGTCACTGCCAACTGATCACCTTAGGCCGGTCACACCATCCCTAACTGGTTTCTAGGAGA CGCTCTCTCCCTCAGTCATGTTGGGTTGTTTCCCCTGATTCTTGGCACCAACCTCAGTAG CTGCTGTAGCCCCATGGCTCTGCCCCCTCACTGAACATTGCGGACCCACAGGTACACAGG CTGGTGCTAGTGGACGAGACCCAGCATCTCTTGGGCGTGGTCTCCCTCTCCGACATCCTT CAGGCACTGGTGCTCAGCCCTGCTGGCATCGATGCCCTCGGGGCCTGAGAAGATCTGAGT CCTCAATCCCAAGCCACCTGCACACCTGGAAGCCAATGAAGGGAACTGGAGAACTCAGCC TTCATCTTCCCCCACCCCCATTTGCTGGTTCAGCTATGATTCAGGTAGGCTCTGCCCTGG GCCATGACACCAGCCTCTTAGTCTTCCTGATTTCCTGGATCTCAGATTGGGACACCCTGA GGATGGGAGTGGCCAAGCTCAAAGCTGAGCAGCCCTGTGAAAACTGCAAGTGTAAGGACT CACAGGTCCCCACTTTGTCCCATTTTCAGCTGAGGTCATGGAGACTGTCCTAGAAGGGAG GGACAAAGCCCCGGCTAAAAGCTAAGGCTGCGATGTGACTTCAGACACTCTGGGAAGATT TACTTGTTCCCTCACAATTCAATTTCCACCTGCTGGAAATCCCCTTAGAAGGAAGCAAGC TATATCAACATTTGTTGGATGGAATTTCCATCCCCAGTAAGAACTAAAGCTTAAAGGAAG GAGCTTCTACCTACGTGCTCATCTCAGGAAATGTGACATGATCTCAGACTCTTTCCTGGT CACACGTTTGCTAGGGGCTTGCAGAGGATGGGCACAGATTCCATCTACTCACCATGGCTG GCAAGGGTCCCCTGTTGGAAAGGCCGCTGTCCCTCCTATGTGGTCACCATCTTCCCTTTT CTTTTCCCCACAGGCTTCTTCAGCCCTCCCAAATTGCCCTTGCCCTACCTGTGCTCCCAG AAGCCCTCGGGCATGCCCAGTGCACCATGGGATGATGAAATTAAGGAGAACAGCTGAGTC AAGCTTGGAGGTCCCTGAACCAGAGGCACTAGGATTACCCCAGGGCCATCTGTGCTCCAT GCCCGCCCATCCCCTTGCCGCCTGACTGGGTCGGATGGCCCCAGTGGGTTTAGTCAGGGC TTCTGGATTCCTCGGTTTCTGGGCTACCTATGGCTTCAGCCTTCAGCTCCTGGGAGTCCC AGCTGTTGTTCCCAGCAACGTCGCCACTGCCCTCCTACTCTCCAGGCTTTGTCATTTCAA GGCTGCTGAAATGCTGCATTTCAGGGGCCACCATGGAGCAGCCGTTATTTATAGAACTGC CTGTTGGAGGTGGGGAGTCCTCCCTCCATTCTTGTCCAGAAAACTCCTTAGCTCTCGCAG TGAGCCATGTTCTTAGTCTCCAGGGATGGATGGCCTTGTATATGGACCCCTGAGAATGAG CAATTGAGAAAACAAAACAAAAGGAACAATCCATGAACTTAGATTTTATTGGTTTCACTC AAAATGCTGCAGTCATTTGACCTGAACTTGTGGCAAGAGACTTGTGCTTTCTAAATTCAA AGACTAGAAGGAAAATGGATAAAAATCACAAGTGCCGTTTCTCTTGC OMIM ID 604976