Entrez gene ID | | 537 |
Official gene symbol | | ATP6AP1 |
Full name | | ATPase, H+ transporting, lysosomal accessory protein 1 |
Aliases | | ,16A,ATP6IP1,ATP6S1,Ac45,CF2,MGC129781,VATPS1,XAP-3,XAP3, |
Gene summary | | This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq28 |
Gene position | | 153656978 - 153664862 Map Viewer |
Gene orientation | | plus |
Gene size | | 7885 bp |
Gene sequence |
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OMIM ID | | 300197 |
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