Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MYO3A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID53904
Official gene symbolMYO3A
Full namemyosin IIIA
Aliases,DFNB30,
Gene summaryThe protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq]
LocationChromosome: 10   Locus: 10p11.1
Gene position26223002 - 26501465  Map Viewer
Gene orientationplus
Gene size278464 bp
Gene sequence
OMIM ID606808