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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DUOX1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID53905
Official gene symbolDUOX1
Full namedual oxidase 1
Aliases,LNOX1,MGC138840,MGC138841,NOXEF1,THOX1,
Gene summaryThe protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q15.3
Gene position45422192 - 45457774  Map Viewer
Gene orientationplus
Gene size35583 bp
Gene sequence
OMIM ID606758