Entrez gene ID | | 53919 |
Official gene symbol | | SLCO1C1 |
Full name | | solute carrier organic anion transporter family, member 1C1 |
Aliases | | ,OATP-F,OATP1,OATP14,OATP1C1,OATPRP5,SLC21A14, |
Gene summary | | This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12p12.2 |
Gene position | | 20848289 - 20906320 Map Viewer |
Gene orientation | | plus |
Gene size | | 58032 bp |
Gene sequence |
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OMIM ID | | 613389 |