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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PMS2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5395
Official gene symbolPMS2
Full namePMS2 postmeiotic segregation increased 2 (S. cerevisiae)
Aliases,HNPCC4,PMS2CL,PMSL2,
Gene summaryThis gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p22.2
Gene position6048737 - 6012870  Map Viewer
Gene orientationminus
Gene size35868 bp
Gene sequence
OMIM ID600259