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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TREM1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID54210
Official gene symbolTREM1
Full nametriggering receptor expressed on myeloid cells 1
Aliases,TREM-1,
Gene summaryMonocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM]
LocationChromosome: 6   Locus: 6p21.1
Gene position41254457 - 41243712  Map Viewer
Gene orientationminus
Gene size10746 bp
Gene sequence
OMIM ID605085