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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for POLR2E (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5434 Official gene symbol POLR2E Full name polymerase (RNA) II (DNA directed) polypeptide E, 25kDa Aliases ,RPABC1,RPB5,XAP4,hRPB25,hsRPB5, Gene summary This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. [provided by RefSeq] Location Chromosome: 19   Locus: 19p13.3 Gene position 1095391 - 1086578  Map Viewer Gene orientation minus Gene size 8814 bp Gene sequence >POLR2E:complement(1026578..1035391):Length=8814 GGATTCGGCGCAGGCGCAGTCCGCGCGGGTTCTCGCGCGGAGAAGGGGTGCGAGCGGCGG CGGCGGCGGAGGCTGCCATGGACGACGAGGAGGAGACGTACCGGCTCTGGAAAATCCGCA AGACCATCATGCAGGTGAGCCGCGCCTGGTGTTGGGGGCGGGGGCGCGGGCGGCGGGTGT AGGGGCCCGAGGTGGGGTCGAGCACGGCGTCTCCTCGTACTCTCGTCGGAGCAGCAGCGA TGAAGGGCCGGGCCGATACGGGAGGCCCAGAGGTCGCCGGGGATACCAGGCGCTGGACCC GACCTGAGCCGGCAGCGGGGAAGGGAGGGGGTTTCGAGACGTCTGGGTGCGGTGCTTAGG GGTGGGTGGGCGGCTTGGGCTGGTGCGGCGCGCGTGGCGGCGAGAGGAGGAGGAAGCCGC GAATGGGGACGGGGGGCGCCCCCAGACTCTGCCCTTCTCTGTGATTCAGCGTCGCTATTT GTCCTTGCGTCCTGAACCCCATGGAGTCTTCAGCATCCGAGGCTGGCAGAGTTGGTGGTT GGGAAGCAGCGGGCGAGCTGGGGCTTTCGATGGGGACGTGGAGCTCGGAACCCGTGCCTT GGGGTCTGGGGCAGATGGAGGCCACTGGGTCGAGTCCGGTTTGGAAGCCGGGCACAGGCC TGAGGACCTGCGGTTCAGGGTATTGCCTCAGCCATTGGGGCCGTTTGAGAGCTTTTGCTT TGTCTTGCTTCCCACCCTTTGCCCTTGTCCTCAGCGAAGCCCCCCGCAGCCTGATTCTTC TTTCTCCGATCCTCAAACATTGTCAGCCTGAAGTCACATCTGTTTCGGTCCCTGTCATTT TTTTTTTTTAAGAGATAGGGTTTCATTCTGTCGCCCAGGCTGCAGTGCAGTGGTGCAATC ATAGCTCACTGCATCCTTGAACTGGCCTCCAGCAACCCTCCTGCCTCAGCCTCCCTAAGT ACTGGGATCACGGGCGTGAGCCTCCGCGCCCCGCCTTTGTCCCTGCCTTTAGGGTAGCTC TGCAAAGTGGTTTGGAGGGCTTTGCTCCCTGCCAGGTTTCTGTGAGGCTGGGTGGACAGA CGGTCTTGGTCAAGGCTGGACATCTCTGGGAGCCTCTCAGGATCATACTGGTCCCATCCT GTGGTGTGAGGCTGTGGGGGCCGGGGTGGCTGTCATGGAGCACACAGTGAGTGTTCATCC CGTTTGCTGTTCACCTCTGTCCTCTGCAGCAGCCGCAGGTCTGACTTCCGGGTCACGAGC TTTGGCCGCCTTCCTCTCTCTGCCCTGGGGTCAGCTGGTTCTTTCTCTCTGCAGCTGTGC CACGACCGTGGCTATCTGGTGACCCAGGACGAGCTTGACCAGACCCTGGAGGAGTTCAAA GCCCAATCTGGGGACAAGCCGAGTGAGGGGCGGCCGCGGCGCACGGACCTCACCGTGCTG GTGGCCCACAACGATGACCCCACCGACCAGATGTTTGTGTTCTTTCCAGGTGAGCAGCGG GTCCCGGGGGAGTTCCGGTGAAGCCACCAGAGCACCTGCCGAGGAGCCGGTCGCTAGCAC CCACCCCCACTCGCCTGGTGCCCAGCATTTGTCTCTCTGCCCAGTCTGGGAGGAAAACTC CCCTCCCCTTCCTTGCTGTGGGTGATGCCGTTGATCTCTGACCCCTCTCATGCTCAGCTT CTTTCTAGTTTCCCTCTCAGTCCCCTTCTCTCTTCCTGCCAACGAGGAGAGTCACAAGGG CCTCCCCACTCACCCCCAGCCCCCCATGTCCTTTGCCCTAGTGTCCCTTGGCTCCCCCAT CCTGGCCGTTGGGTGCACTTCCAGCTTCTTGGCCTGGCCCAGGAGGCCCCGTCTGGGTCA GCGCAGCCTCCTTGTGAGCTGCGGCCCCTGCCCGCCCCAGCCCATTCCTCCGCACCCCAT GCCCCCTCTCCCCTGTCAGCGTCCGGTACTCGTCCCTCGAGCTTGTGCTCGGGCCTCTTT TCCCAGGACCCCTGGGACCCTCGGTTTCAGCACCTGCTTTGCGGAAGTCTCCGCACCTGT CTGCCTCCCTAGTATGGCTCTAAAGCCCTCAGCGGTTGGGGGATTGCAAGCGCCTTAGGG GCGCAGCCCCACGCCCAGAATTAATCAGTGGGGTGACGGAGCACGTCTGCCAACCGGACC TGGTGACGCTGCTGGGTTTTTTTGTTTTTTTTTTGTTTTTGTTTTTTGAAAAAGAGTCTC AATCTGTCGCCCAGGCTGGAGTGCAGTGGTGCCATCTCGGCTTGCTGCAGCCTCCACCTC CTGAGTTCAAGCGATTCTCCTGCCTCAGCTTGAGTAGCTGAGATTACAGGCACCCACCAC CACGCCTGGCTAGTTTTTCTTTGCATTTTAGTAGAGATGAGGTTTCACCATGTTGGCTAG ACTGCTTTCAAACTCCTAATCTCAGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGG ATTACAGGCGTGAGCCACCGCGCCCAGTCTTTTTTTTTTTTTTTTTTTTTGAGACTGAGT CTCCCTCTGTCACCCAGGCTGGAGTGTGCAGTGGCGCAATCTCAGCTCACTGCAACCTCC ACCTCCCAGGTTCAAACAATCCTTCCACCTCAGCCTCCCAAAAAGCTAGGTTTACAGGCA TACACCATCTCACCTGGCTACTTTTTCTTTTTGTATTGTTTATTAATTAATTAATTAATT TTTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATCTCTGCC CACTGCAAGCTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCT GGGACTGCGGGCGTGGGCTAATTTTTTGTATTTTTAGTAGAAACGGGATTTCACCTTGTT AGCCAGGGTGGTCTCGATCTCCTGACATCGTGATCTGCCCACCTTGACCTCCCAAAGTGC TGGGATTACAGGTGCGAGCCACCGCGCCCATCCTGTATTGTTAATAGAGACCGGGTTTCA CCATGTTGGCCAGGCCGGTTTAGAACTGTTGACTTCAAGTGATCCACCTGCCTCAGCCTC CCAAAGTGCTAGGATTACAGGTGTGAGCCACCGCACCCGGCCTCAGGTGATGCTTCTTAA AGAGAGCGTCCTGGGGTGTGAGGTCTGCTTGTTGGAGAGGTTGGTGCTGAGTCACCCGCC TCCCCAGAACTGCCCAGGGTGGGAGCCTCTCAGAGTCGAAGGTCTCTGCTTCTCCCTGGT CTCTGGGTGACTGAGGGGTGTCAGCCCCCTGTCCCTGTCTCCGGGTGAATGAGAGGTTTC AGCCCTCTCTTCCCCTGTCCTGGGATCCTGCAACTCAGGCCTCGTTTTGCAAACGCGGAA GCCGAGGCCCGAGCAGGAGAGACACCTGTGTGGAATGGGGCTGGAACCTGGGTGCTCTGG GCTCTGGGTGGGCGAGGGCCACGAGGGCCCAGGCTCGTGCAGGCCAGCACACTCTCTGTC TGCAGAGGAGCCCAAGGTGGGCATCAAGACCATCAAGGTGTACTGCCAGCGCATGCAGGA GGAGAACATCACACGGGCTCTCATCGTGGTGCAGCAGGGCATGACACCCTCCGCCAAGCA GGTGGGCACCCCTGCCCCACCCCGCCAGCCTCTCCCCCTCCCCAGCCTCCTCCCGCAAGC AGTACCCACAGGCGGCCCACGTGCCTTGGGCTTTGGGCCAGGCCAGCCAGGGTGCCCTGG AGGATGTGGCCGGGATGTCCGGCAAGCCCCGACCGCCTCCCTCCCACCGCGTCCATGGGC CCCACCCCAGGCAGCCGCCGTCCTCCCCCAGCTCTCAGGAGGGGCGTCAGGGCGGAGGGC ACTGTGCCTCTCGCCAGCTCCTGTGGGCTCCAGCCCTCGGCCTGGTGCAGATTCCAGGAG CCGGAGGTTCTTTATCCTGAGCTGATGTCCAGGGGGACTTGCAGAGGAGGCCCGGCACGG GGTCCTCCAGGGGCCTATCCGTGTTCCCCGTCTGTCTGTCGGACACTCTGGAGCCAGGCT GCTGTGCTGTGACGGGCAGTCAGCAGAGCAGTTTAGTCCCTGGCCCACCAGCTGTGGGGT TCACGCAGCCACACAGAGCAGCACCCCTGTATGGGGAAGAGGTCGCCCTGCCAGCTCTGA GGGCCGCCCCTGGAAGCGTGTGATGGATGGAAACACATCCGAGTTTCCACGGCCACTTCA CTGCTGGATGAGGCTCTCGATGAGCAGAGAGGCTGGGGAGGGGCGGGCTGTTGAAGGCTC CTGGGCTGGCGGTGGGGTTTTCTGATTCACGACGTGGGTGTGTTGTTGGGGCACACGAGT AAGCCCCAGGTAGCTTGAGGCAGGAAATGGGGTTGGGGTTGTCTGGGCCCCTCCGGGCCG TGCCTTAGAGCCGCTCTCTTCCAGTCCCTGGTCGACATGGCCCCCAAGTACATCCTGGAG CAGTTTCTGCAGCAGGAGCTGCTCATCAACATCACGGAGCACGAGGTGGGCGCGCGCCGC GGAATCCCGCCTGCGTGGGGCCGGCAGAGATGCAGCGTTTGTGGGTGGCCAGGAAGATGT GGGATCTGGGGCCCAGGGCAGGTGTTCCTATTAGTGCATGGAGGACAGGGTTCTCAAAGG GTGGCCCTGGGCCTGCAGCAGCCGAACCCGGGAGCTTCCTAGAAATGCAGATCCCGGCCG GGCGCGGTGGCTCACACATGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACG AGGTCAGGAGTTCCAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATA CAAAAAAATTAGCCAGGCGTGGTGGCGAGCGCCTGTAGTCCCAGCTACTCGGGGAGCCGA GATTGTGCCACTGCACTCCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAAAAAAAA AAAAAAAAAAAATGCAGATCCCGGGCCCACCCCAGCCTGTAGAATCGGGACTGCTGGGAG TGTGGAGGGACCCTAGTGCTGGGACAGGAGGAGTCCCAGCAGGAGGTGGCTGTGCCCAGC CCGTCTGCCTCAGAAGCCCCAGGAGCTGTGACTCCGTCCCCCGCCTGTGGAGCCAGGGTG GGGTGGGTGGGCTCCCTGAGTGCCGGGGATCGGGGTGGGGTTCAGGGCTCTTGTCCGTCT GAAGGCGCAGGGGCTGTGGTGGCACCTGGGAGCCACGTGGGGTCTCACCAGCCCTTGGTG ATGCCTGGTGGCTTCCTCTCTCGGCAGCTAGTCCCTGAGCACGTCGTCATGACCAAGGAG GAGGTGACAGAGCTGCTGGCCCGATAGTATCCTTTCCAGCCCCACCGGCCCCGCCCCTCC CTGTCCCTCGAGACTTCCGCGTTCCCCCCCCACACACACCCCTGCCCCCCCAACGGCCCT GTCTGGCATTTTCCTGACGGTGCTTCGCAGTAAGCTCCGAGAGAACCAGCTGCCCAGGAT CCAGGCGGGGGACCCTGTGGCGCGCTACTTTGGGATAAAGCGTGGGCAGGTGAGCCCTGT GGGGAGAAGGGGCCCTGGGGCTGCTCTGAGCTGACCACTCGGAGAAGGGGGCTTCTGTCC CTCCCCGACAGCCCCTCCCCCTTGATCCAGGGCCTGGAGGGGACCTCGAGACCACACCCC CAATATCCCCCTCTTAAAGCCAGGGCCACTGGGCCCAGAGAAGAGCGTGACCCAGGTTCC CAGGGAGCGGGTCCCACAGCCCAGGGTCAGCCATCTCGGACCCCTGCCGGCCATCCCCAG CCCGTGTGCTGCCCGCCTGCTGTCTGGTGACTGCAGTGAGACCCCTCAAGCATTCGCAGC CCCTGCTCTCTGTCTCTGCAGGTGGTGAAGATCATCCGGCCCAGTGAGACGGCTGGCAGG TACATCACCTACCGGCTGGTGCAGTAGCTACCGCCTGACAGGTGAGACGGCCGAGGGACA GGCACTGAGGTGGGGTCAGAGGCAGGGGTGTCGTCCCCTCCGTCGGTGTGCAGGGCTGTT CTTGCTTTGTCCGGCAGCAAGACCCTCCTAGCACCAGCCCAGCTGGGCCACCAGGCGCTC CCAGGACACCCCCAGACCCCCAGACCCCACCCGACCGTAGGCTGCAGCTCTTGGGGCTGT GCGCCTGGACGGGAGAGTCCTGGTACGCGGGGCGTGCGTCTCTCCGCCGCTGACCCACCT TAGAAGCAGGAGACGTTCACCTGCAGGGCAGTTGTGCGGCGGGACTTTCCAGAAGAGGGT TTAGAAACCTGCCCAGAGACCCCAGAGCTGAGAGAGGAGGCACAGCTTCAGGCCAACCCT TCCCTGAGTGGGCACCTTGGGAGGGACTGGCCGGAGTCTCAGGAGCGGGACAGCCTCTGC CCATGGCGAGAGCCTCCCAGCTTCCCCTGGACTCTGGTCATGGCGAGCTGCTGTCCTGCA GGCCGCCCCACTTCACACTCAGCCCAGGGGTGGGGCTTGGCCTGGTCTGACGCTGGCACG GTTCCTTTGAGGTCAGAGCTACTGCCCACGCCTGTGTGACCGCTGGGCACAAGGGAGCCG TCCGGCCTCTGCACTGCGGCCTGGGCCGCCTCCTGCCAGGCCTCCCGCACCCCGTCACGT TCGGTGGGCGTTGTGCTGTCCTGGGCATACTGGATCTGCCCCTGTCGTGTGACCACTCTC CCCCTTTCCTAGCCCCTAGAGGCGGACACACAGCGACCCCCATCCCTGCAGGACAAACGC CCCTGCCCTGCCAGAATCCGGCCCCCACAGCTCTCACGGCTGCTGCTCCTCTGGACTCCC CAAGGCAGGTGGCCTCCACCCACGTTCTCCCGTCCTGGGGTGAGGCTTCCTGTGGCCCAG CCCGCCCCATTCACCTGTGGATTTGTGCGAGATGCAGCCTCAGAAGGAACAAGGCCCCCA GAGGGAGGTCACCTGGGGGCAGCTGGTGCCGGGTCTTCACCCAGACCACGCTGGGTCCCC TCTGTTGGGGGTTTGGGGTCCGGGTCTCCCACCAGCCACTGCTTCCTCCTGGGCCCTCGG CCTTCCACCCCTCGTCTTCCCTCCCTCGGGGGCCCTGATGCGTGGCGGCCCCCGCCCGGC CTCGGCTCTTTACTCCATTCACAGCCATGCACGCGCTCAAGCCACCAGGGTGCGAGATGC CAGCTCTGGAGTTCTCGGTTGTTGTAGGAGGTTGGGTGTTTTCAAATGGTAAAGATGTTT TGAGCAAATAAATTTGCTTGATACAGAAACCAGGCCGACTAACAAGGTTTCCAGCAGGTG GCCTTGCCTCACCCCAAGCACACGAGGTCAGCCTGGCAGGTGTGCCCTCCTCGCGCTGGC TTCAGGGGTCAGTGTCTCCCCAGGCCCTCGCCCTGCCCTCCCACTTCGTGCTCCTGGGTA AGGCGTGAGCGTGTCTGTCTCTTCCCTTCCCGTGAGGGTGTGGAGTTGTTCTCTGGCTTG TGCAGCTGTGGTTTGCGGCCAGTTCCTCTTACAGACGTTTGGGATCTGGCTCTACTTCCC CGTTTGCTTACTGTCTGATTTCAGAAGGCCTCGCCTGCCCAAGTTTAACCTAGCCACGTG GTTCTCTCACAGTAGCTTTATTAAGATGTAATTCACCCTCGGGCGGTCGGTGGTCTGTAA CGCGCCCACTGTTCTGTGCAGCAGGGTCCCCAGATCCCCAGGCCGCGGACTGTGTGTGTG ATGGGGACAGTGCTTCCCCTTCTCTCCAAATGTACTTTTTTCAAAATTGTCTTGGCCAAA GCAAGCCAGACCCAAAGGGACAAACACTGATGTCACTCCTAGGAGGTCACTAGAGTCGTC AGAGACTGGAAGTAGGATGGGGGTTCCCGGGACTGGGGAGTTGGGTGGGGATGGGGGTTC CCAGGGCTGGGGAGGAGGGAGGGGACAGAGTGTGTCATGTGCACAGTTTTAGTTTGGGAA GATGAGAAAATTCTGGAGGTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTT GGGAGGCCGAGGTGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACAT GGCAAAATCCCATCACTGCAAAAAATACAAAAATTACCTGGGCGTGGTGGTGCATGCCTG TAATCCCAGCTACTTGGGAGCTAAGGCAGGAGAATCACTTGAACCCAGGAAGTGGAGGAT CGCTTGAGCTCAGGAGTTAAAAGACCAGCCCGGGCAACACAGAGAAACCCCCCACCTCTA CAAAAAACTTTAAGATTACCTGGGCACAGTGGCTCACACCTGTAATCCCAACACTTTGGG AGGCTGAGGCGGGAGGATCATTTGAGCCCAGGAGGCCGAGGCTGCAGTGAGCTACGATTG TGCTCCTGTACTCCAGCCTGGGCCACAGGGTCACACCCTGTCTCAAAAAAAAAAAAAAAT GCAGTTCCACAGGCGCATGGGCCACGTTTCCAGTGCTTGGTGGCCATGTGGGGCTGACGT GCGAAACCTTAGAGCCGGGGGATACGTCCGTCATCGAGAACGTTTTCCTGGACTGCCCTG GGCTGCAGGTGGACGTGACGAGGTCATTCGATGCCTGACCGTCTGCACAGCCTGTGGTGA AGACCACCCGGGCTCCCACCTCGCGGGGCCCCGTGGCGGGGGGTTCCCTTCCTCACACAT CCCTCCCCTAGGGGGAGGCCCAGGGCCACGCCACGGGGCTCTCTCTGTCCCCTCCCTGGC CCCTTCTTCTAAGCTTGCAGCTGCCACAGAAAATCTTCTAAGCTTGCAGCTGCCACAGAA AACACCCGATTAAAAACTTTTTATTTCAGCAAAATAAACGTGCCTGTGAAAGAA OMIM ID 180664