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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ING3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID54556
Official gene symbolING3
Full nameinhibitor of growth family, member 3
Aliases,Eaf4,FLJ20089,ING2,MEAF4,p47ING3,
Gene summaryThe protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q31
Gene position120590817 - 120615711  Map Viewer
Gene orientationplus
Gene size24895 bp
Gene sequence
OMIM ID607493