Entrez gene ID | | 54677 |
Official gene symbol | | CROT |
Full name | | carnitine O-octanoyltransferase |
Aliases | | ,COT, |
Gene summary | | This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described. |
Location | | Chromosome: 7 Locus: 7q21.1 |
Gene position | | 86974951 - 87029112 Map Viewer |
Gene orientation | | plus |
Gene size | | 54162 bp |
Gene sequence |
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OMIM ID | | 606090 |