Entrez gene ID | | 54843 |
Official gene symbol | | SYTL2 |
Full name | | synaptotagmin-like 2 |
Aliases | | ,CHR11SYT,EXO4,FLJ21219,FLJ34802,FLJ42764,FLJ45597,KIAA1597,MGC102768,SGA72M,SLP2,SLP2A, |
Gene summary | | The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Location | | Chromosome: 11 Locus: 11q14 |
Gene position | | 85522178 - 85405264 Map Viewer |
Gene orientation | | minus |
Gene size | | 116915 bp |
Gene sequence |
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OMIM ID | | 612880 |
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