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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPM1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5495
Official gene symbolPPM1B
Full nameprotein phosphatase, Mg2+/Mn2+ dependent, 1B
Aliases,MGC21657,PP2C-beta-X,PP2CB,PP2CBETA,PPC2BETAX,
Gene summaryThe protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p21
Gene position44396000 - 44461742  Map Viewer
Gene orientationplus
Gene size65743 bp
Gene sequence
OMIM ID603770