Entrez gene ID | | 55008 |
Official gene symbol | | HERC6 |
Full name | | hect domain and RLD 6 |
Aliases | | ,FLJ20637, |
Gene summary | | HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM] |
Location | | Chromosome: 4 Locus: 4q22.1 |
Gene position | | 89299891 - 89364249 Map Viewer |
Gene orientation | | plus |
Gene size | | 64359 bp |
Gene sequence |
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OMIM ID | | 609249 |
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