Entrez gene ID | | 5511 |
Official gene symbol | | PPP1R8 |
Full name | | protein phosphatase 1, regulatory (inhibitor) subunit 8 |
Aliases | | ,ARD-1,ARD1,NIPP-1,NIPP1,PRO2047, |
Gene summary | | This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p35 |
Gene position | | 28157293 - 28178183 Map Viewer |
Gene orientation | | plus |
Gene size | | 20891 bp |
Gene sequence |
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OMIM ID | | 602636 |