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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPP2R1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5519
Official gene symbolPPP2R1B
Full nameprotein phosphatase 2, regulatory subunit A, beta
Aliases,MGC26454,PP2A-Abeta,PR65B,
Gene summaryThis gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q23.2
Gene position111637169 - 111597632  Map Viewer
Gene orientationminus
Gene size39538 bp
Gene sequence
OMIM ID603113