| Entrez gene ID | | 5523 |
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| Official gene symbol | | PPP2R3A |
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| Full name | | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha |
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| Aliases | | ,PPP2R3,PR130,PR72, |
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| Gene summary | | This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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| Location | | Chromosome: 3 Locus: 3q22.1 |
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| Gene position | | 135684515 - 135866752 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 182238 bp |
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| Gene sequence |
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| OMIM ID | | 604944 |
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