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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPP2R4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5524
Official gene symbolPPP2R4
Full nameprotein phosphatase 2A activator, regulatory subunit 4
Aliases,MGC2184,PP2A,PR53,PTPA,
Gene summaryProtein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34
Gene position131873228 - 131911225  Map Viewer
Gene orientationplus
Gene size37998 bp
Gene sequence
OMIM ID600756