Entrez gene ID | | 55247 |
Official gene symbol | | NEIL3 |
Full name | | nei endonuclease VIII-like 3 (E. coli) |
Aliases | | ,FGP2,FLJ10858,FPG2,NEI3,hFPG2,hNEI3, |
Gene summary | | NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM] |
Location | | Chromosome: 4 Locus: 4q34.3 |
Gene position | | 178230991 - 178284092 Map Viewer |
Gene orientation | | plus |
Gene size | | 53102 bp |
Gene sequence |
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OMIM ID | | 608934 |