Entrez gene ID | | 553 |
Official gene symbol | | AVPR1B |
Full name | | arginine vasopressin receptor 1B |
Aliases | | ,AVPR3, |
Gene summary | | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q32 |
Gene position | | 206224283 - 206231482 Map Viewer |
Gene orientation | | plus |
Gene size | | 7200 bp |
Gene sequence |
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OMIM ID | | 600264 |