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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPP3CC (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5533
Official gene symbolPPP3CC
Full nameprotein phosphatase 3, catalytic subunit, gamma isozyme
Aliases,CALNA3,CNA3,PP2Bgamma,
Gene summaryCalmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]
LocationChromosome: 8   Locus: 8p21.3
Gene position22298596 - 22398638  Map Viewer
Gene orientationplus
Gene size100043 bp
Gene sequence
OMIM ID114107