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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXL8 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 55336 Official gene symbol FBXL8 Full name F-box and leucine-rich repeat protein 8 Aliases ,FBL8,FLJ11278,MGC19959, Gene summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq] Location Chromosome: 16   Locus: 16q22.1 Gene position 67193891 - 67198077  Map Viewer Gene orientation plus Gene size 4187 bp Gene sequence >FBXL8:20808090..20812276:Length=4187 GCTTCCCGTCCGCTGTCCTCTGCTGCCAGTCCCCTGCCCCGGGCAAAGCCCATCTGGTCC GCCGAGCAGGTAAGACACCAGCGCCCAAGGTTAGACGGCAGGAAGACCCGACTTTGGGGG TTTGCGATTCTTACGAGGCGGGGGGCTCGTAAGAGCTACAGCTGCCAGACTTCGGTAAAT CAAGGGGGCGCCCCCTGGAGACCAGAATTTTCTGGTACCCCTGGGGATCCGGCTTCAAGA TCGCTGCTACCAGTGGGCACTCAAAACGGGGTGCCCATGGGTCCCAGGTACAAGCCCGGC CGAACGTATCTGAAGCCCCAGGAAACACGTGGCACAAATTCCGGGAGAAACTGTTAGCCC GGAAGATATGGGAACATTAACTGGCGAGTAGTGTGAAGCCTTGTGTACACAAACCTTTAA GAACCTTAAAACAAGATTGGCGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTT TGGAAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAATA TGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCCGGCGAGGTGGCGCGCGCCT GGAGTCCCAGCTACTCGGGAGGCTGAGGCAGAAGAATCGCTTGAACCCGCGAGGCGGAGT TTGCAGTGAGCCGAGATCTCGCCACTGCACTCCAGCCTGGGCGACACAGCTAGATTCCGT CTCAAAACAAAACAAAACAAAAACAAACAGGATTGGCAACTTCAAAGAGGACGCACACTT TCCAGTAACCCATCCCCCTCTAAAGGCTGCGCTCCAGGGTGGGTCTGCGGAGTTCCAGCC GAACCCAAATTGCTCAGCGGGAGCCAGGGCTGCTCAGGGGTCGGAACTTAAATCTTGAGC CCCTCAGGCCCCAGAACCGTCAGGTCCCAGAGACCCAAGTTTTTTTTCATCCAGTGGGGC TGTCTTAGGAAGCACCCGGGACATCTCCCCGGCGAGGCGGAGGCGGGGAAGGAGCCTCCC CTCCAGGGGTGGATCCAGCTTTGCCCCGCCCACGCCTCGCTTCCTGATTGGCTCATGGTC CCTGACAAAGAAAAGCCTACATTAACGCTCCCGCCTTATTAACCCTGTAGTCACTTTCTA CTAACCGGCGGGGTTAAGATGGGGTTTCTCAGGCCGGGCGCGGTGGCTCATGCCCGTAAT CCCAGCACTTTGGGAGGCCCAGGCGGGCCGATCGCTTGAGCCTAGGAGTTCGAGGTCAGT CTGGGCAACAAAGCGAGACCTCGTCTCTGCAACAAAATTACAAAAATTAGCCAGGCGTGG TGGCGTGCCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCC GGGAGACTGAGGGTGCAGTGAGTTGTGATTGCGCCACTGCACTCCAGCCTGGGTAAAGAG CGAGACCCTGTCTCAAAAAAAAAGAAAAAAAAAAAAAAAAGTGGGAGGGGAGTTCTCAAC GTGGAACCTGTGGAGTCACAGGGGCTTGTTGAAATGCAGATTCCTGGGCCTTACCCTTTC CGGAGAGCCTGATTTAGTAGGTGAGGCGGTGAAATCTGCTTTGTGAACAAGTTTCGGGGT TATCTGATGCCCCACGCTGTCTGAGAGGCCCTCAGTTCCTCAGGCCACAAGCATTTGTAC ACCTAAGCTCGGTCTTCCTGCAACACTTTGCGCCTTCCCGACCTCAGAGACGTCCGTCTC TCTCCAGGCCGGAGCTATTGGGAGTGGCGGATCCTCCCACCCCAGCCGGATCTGGGCCAT GGCCGAGCCTGGAGAGGGACTGCCAGAGGAGGTGCTGGCACTCATCTTCCGCCACCTGTC CCTGAGAGACCGTGCTGCCGCCGCCAGGGTCTGCAGGGCCTGGGCCGCCGCTGCTACCTG CAGCGCCGTGTGGCACGACACAAAAATCAGGTGAGCCTGCTCCTCCACACTCCTCTCCCC ACCGCCCACTCACCTTCTCCGTGGAGTCGTGGGCTAGGTAGATATTCAGGTTGACTCCCC CATATTAAAAAATAATTGCTGGCCGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTT GGCAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCACCAT GCTGAAACCCCGTCTCTACTAAAATACAAAAACTAGCCGGGCATGGTGGTGGGCGCCTAT AATTCTAGCTACTCGGGAGGCTGAGGCACAAGAATCGCTTGAACCCGGGAGGCAAAGGTT GCAGTGAGCCGAGATGGCACCACTGCACTCCAGCTTGGCGACAGAGTAACAGTTTATCTC AAAATAATAATAATAATTGCTGACGTATTGACTGCCTAGTATATACCAACCATTGTTTTT AAGTGCCTTACATATATTAACTAATTTAATCCTTATGAAAACCTTGTGTGGTAGATAGGT ATTATCATTACCTCCATTGCCCAGATAGGAAACTGAGGCAAAGAGACTTAATCACTTCCC ACGGGTCACTCAGCTAGGGAATGGCAGAGGCAGAATTCGAACCTAGCAGTCCGGAGGCCA TGCCAAGACTCCTTAGAGACAGCTGAGAAAGCCCAGTTCCTAAAATATCATTGGCTCTCC ATGTCCAGGTTTCATCCTGTGGCAGACGCCACTGAAATCTTCTAAAAGGATAGGATGCGA GTTCCCTCCTTTGGGGCAACAGTCGTGGTCTGAACAGAGACGTGGGGAGGGAGGCAGGAA ATGGGATGGCAGCTGGAACCCCAGCTAAGGGGTGGGTAGAGGCTTCTCCGCTGGTCGCAG GGACTCAGCTGAGGCCTTTTCTGCACGGCTCTAACCCAAGTTGCGAATGTGAGCTGGAAG GCATGCTGCCACCTTATCTGTCCGCCTGCCTCGACCACATTCACAACCTACGGCTGGAAT TTGAGCCATCGAGGAAGCCGAGCCGCCGGGCGGCCATCGAGCTGCTGATGGTTCTGGCGG GCCGTGCCCCGGGGCTGCGAGGCCTGCGCCTGGAGTGCCGCGGAGAAAAACCGCTCTTCG ACGCGGGCCGCGACGTCCTGGAGGCTGTGCACGCTGTATGCGGGGCGGCCAGCCAGCTAC GCCACCTCGACCTGCGGCGCTTGTCCTTCACACTGGACGACGCGCTGGTGCTGCAGGCGG CGCGCAGCTGTCCCGAGCTCCACAGCCTTTTTCTGGACAACAGTACCCTAGTGGGCAGCG TGGGTCCCGGCTCAGTGCTCGAGCTACTGGAGGCCTGCCCGCGCCTGCGCGCTCTCGGCC TGCACCTAGCCAGTTTGTCGCACGCCATCCTCGAAGCACTGGCGGCGCCAGACCGAGCGC CTTTCGCGCTCTTGGCTCTGCGGTGCGCGTGCCCCGAAGATGCACGCGCGTCCCCGCTGC CCAACGAAGCCTGGGTCGCGTTGCGCCGCCGCCACCCTGGGCTGGCAGTGGAGCTGGAGC TGGAGCCCGCGCTGCCCGCTGAGAGCGTGACGCGCGTCCTGCAGCCAGCCGTCCCCGTGG CTGCGCTGCGCCTCAACCTCTCAGGCGACACCGTAGGCCCAGTGCGCTTCGCAGCACACC ACTACGCCGCAACCCTGTGCGCGCTCGAGGTGCGCGCAGCCGCTTCGGCCGAGCTGAACG CCGCGCTGGAGGAGCTGGCGGCGCGCTGCGCGGCCCTGCGCGAGGTGCATTGTTTCTGCG TGGTGAGCCACTCGGTGCTGGACGCCTTCCGCGCGCACTGCCCGCGCCTGCGCACCTATA CCCTCAAGCTCACGCGCGAGCCGCATCCCTGGAGGCCTACGCTCGTGGCGTGATTGGGCG ACTTCTCTCCCCCGTCCCCGTGGACGTAAGCGCTCTGAGAGGGAACGGGGGGGGTGTCCA GGCGCGCCCCGAGTGCTAGTGCCTTCTTTTGGGATTGTTGCCCCCCGGGTCTTTACCGAG TTGGGAACTGTGATGGCATCGGGACCAGTCCTGGGCGCCCTGAGACCACTCGCTGCTCTC ACCCTCTGCAGACGCCCCACCCGCTCGGTCCTGGACACACTGCCCCCCTCTCTTGCCTCC ACCCCTCTGCGGACTCTGCAGCTCCGCGGCCCCGGCGCAGGGAGAGGGAGGGCACGGGCG CGGGCCGGGCCTCAAGGGTGAGTGTGAAATAAACAAATCCTGCAGTG OMIM ID 609077