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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PIDD (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 55367 Official gene symbol PIDD Full name leucine-rich repeats and death domain containing Aliases ,LRDD, Gene summary The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq] Location Chromosome: 11   Locus: 11p15.5 Gene position 805250 - 799179  Map Viewer Gene orientation minus Gene size 6072 bp Gene sequence >LRDD:complement(739179..745250):Length=6072 AACGCGCCGGCGGGATCCCAGGCGCCGAGCGCCCGCTGAGCAGCCACCCTTTGCGCGCCG CCTGCAGCGCAGGTACGCGCCGGCCTGGGCGGGCGGAGGGGGCGGCGGGGACACGTTTGC TTTTGGGAGGCTGGGGGCCGTTCCCATCCCCGACGCCCGGGGGATCCCGAGCCTGCCTCG GGGCTGGGGCCCGCCCCCCACGCCGTCTGAGCGGTGCGCGGTGCACCACCCTCCCCAGTG GACCGAACTGGAAAGGCCGGGAGAGGTTTCCTCCGGGGCTCACGAATTGGGGTCCCGGCC CCAGGACCCCGAAGCTGCCCAATGGCTCACGCCCCAGGCCCTCACCCTTACACGGCCTTC CCTGACTTTCGGGGCGCAGTCACCCCCGCGGTAGGGGAGGGTCACGGCCTTCCTGGTAAA ACGGATGTAAATAGAAGGGGGACTCATCTCCAGGACTGGGGAACAGCCCCTATGACCTCG CAGCTCCACGGCTCCATTGGCCAGATTTCCAGGACCAGGACTGAAGCCTCACTACCCCGG CTTTGCTGCTCATAGCGAGGTCTCCCTGCCCGGTGCTCCTGCGAGCCATGGCGGTCCCAT TCCCCAACCCTCTTTCCAGTGGTGACCCAGGCCTCCGGGGTTCAGGGTGACCACAAGGTC TCCCCCACTCTGCAGCCCAGGCCCAGATGGCCTGGCTCTAGAGCTCCCCACTCCATCCAG AGTCCCTGTTTCCCCAAAGAGAAGGGCCCACCCCGGCTCCCGCTCACTCCTCCTCCTGCC TCTGCAGCTTCCCCGGGCGCTGCCTGGACAGGCCTGCCTGCGTGCTGGGACATGTCTGGC CTCCAAGGACCGTCGGTGGGCGATGGCTGCAACGGTGGAGGGGCCAGAGCTGGAGGCAGC TGCTGCCGCAGGAGATGCTTCAGAGGATTCGGACGCAGGGTCCAGGGCGCTGCCTTTCCT GGGCGGCAACCGGCTGAGCTTGGACCTGTACCCCGGGGGCTGCCAGCAGCTGCTGCACCT GTGTGTCCAGCAGCCTCTGCAGCTGCTGCAGGTGGAATTCTTGCGTCTGAGCACTCACGA GGACCCTCAGCTGCTGGAGGCCACCCTGGCCCAGCTGCCTCAGAGCCTGTCCTGCCTCCG CTCCCTGGTCCTCAAAGGTGAGTTCCACCTGTTCTGGGCCCTGTCTCCATCTCTCGCTCT GCCCTGCCTCTGCTGCATGTTCTCAAAGGCAAACCCCAGTCCCAGCCCCAGCTCCAGGCC GCCCCTCCCGGCTCCCCAGGTGTGAACTGTTCTGCTCTTGGTCCTGTCCAGCCCCATCGC CATCCTCGGTGATCACCACCCCCAGTGTGGGGCTGGCTGGGCCCTGGCTCCTGGACCCTG ACGCTGCCCAGTGGGGGTCTCTCCAGACCACAGTGCAGATGTTGTTCCTGGGGAAGGTTG TGGGTGATGGTTGTCAGCTGAGATGAGCCGGTGGTCTCCACCCCTGCCTCCTTCCATTTG CGGGCACCTCTCCAGTGTTTCTGTCTGTCTGTCCCTGTCTGGCTGGGGTGGGGGTGGGGT GGGAGGTCTGTGCCTCTCGAGCAGCTGTTTCTCTGGCTGGCAGGGTCGATCTGGGACCTC GGACCCTGGCTCTGAGGGCCACATCCGCCTCCCCCCTTCCCAGGAGGGCAACGCCGGGAC ACACTGGGTGCCTGTCTCCGGGGTGCCCTGACCAACCTGCCCGCTGGTCTGAGTGGCCTG GCCCATCTGGCCCACCTGGACCTGAGCTTCAACAGCCTGGAGACACTGCCGGCCTGTGTC CTGCAGATGCGAGGTCTGGGTGCGCTCTTGCTGTCTCACAACTGCCTCTCTGAGCTGCCT GAGGCTCTGGGGGCCCTCCCCGCCCTCACCTTCCTCACAGTGACACACAACCGCCTGCAG ACGCTGCCCCCAGCACTGGGGGCCCTATCCACCCTGCAGCGCCTCGATCTCTCTCAGAAT CTGCTGGACACGCTACCTCCTGAGATTGGAGGCCTGGGCAGCCTCCTGGAGCTCAACCTG GCCTCCAACCGGCTGCAGAGCCTCCCAGCCTCTCTGGGTGAGTAGCCCCTGCGCCCCGAC ACACTGGCCCCACGGGAGGGTCCCTGAAGCCTGCCTGTCTTCTGCAGGGGCCTCTGCACC CACAGGCTTGGTCCACAGCTGCCTCTTGGTTGTCCCTCCACCTCCCTGGCCTTTGAGACT CCCTCAGTGGCTTTGTCAGAGTTCTCTGAGCCCAGCTGTGGAGGAGAGTCTGAAACAGCT GCTCTGGGAGGCGGCAGCAGGAGTGTCCCAGCGCCGTGGGCTGGGCTGGTGCCAAGCCTA AGCCAGCAACTGCCCGCAGCGGGACTTCGGTCCTTGCGGCTCCTTGTCCTGCACAGCAAC CTCCTGGCCTCTGTGCCAGCTGACTTGGCCCGCCTTCCACTCCTCACCCGGCTCGACCTG AGGGACAACCAGCTCCGGGACCTGCCCCCTGAGCTGCTAGACGCCCCCTTTGTGCGCCTG CAGGGGAACCCCCTGGGTGAGGCCTCGCCAGACGCCCCGAGTTCACCAGGTAGGCTTGGT GCTAGAAGGGGCAGACCTGGGATAGGACATGAGTCTCCTCACTGTCCTGAGCACATGTCT GTCCCCTGCACAGTGGCAGCCCTCATTCCAGAAATGCCCAGACTGTTCCTGACCTCAGAT TTGGACAGGTATGGGGTGGGTTGAGGGGGCTGGAGGGGAGTCTGTCTGCCTGTCACTCTG GCCCCTCCGACACCTTCTCCAGAGTTCCTGGGTCCAGGCTCCAACACGTAGGCCCTTCTG GGTCTAACCTGTTGCTCGCTCCTTCCTCACTCAGCTTTCCTGTGACCCCTCAAGGCTGCT CAGTGACCCTGGCCTGTGGCGTCCGCCTGCAGTTCCCAGCGGGAGCCACCGCCACCCCCA TCACCATCCGCTATCGGCTGCTGCTGCCGGAGCCAGGCCTCGTCCCCCTGGGTCCTCATG ACGCCCTGCTCAGCCATGTGCTGGAGCTGCAGCCCCATGGGGTGGCCTTCCAGCAGGCAT GGACAGGGCGTGGCGGGGGCAGTGTGTGGGCCAGGGCATGGCAGGGGCAGTGTGCGGGCC CGGGCATGGCTCCAGTGCTCACACCATCCTTGTCTGGCAGGATGTGGGGCTGTGGCTGCT CTTCACCCCACCGCAGGCCCGGCGCTGCCGTGAAGTGGTGGTCAGGACCCGGAATGACAA CAGCTGGGGTGACCTGGAGACCTACCTGGAGGAAGAGGCACCCCAGGTGAGGGCCACCCA GGCCTGCCGGTGGCGAGTGGAGAGCTGCTGCCCTGAGCCGTGCACCTCTGCCCAGAGCCT CACCCTGGCACCTTCCACCCTGCCCCGTCCCTCCTGGATCCTGCTTCCCTATGTCCCTGG CACCTTCCACCCCACCCCGTCCCTCCTGGATCCTGCTTCCCTGTGTCCCTGGCAACTTCC ACCCCACCCCGTCCCTCCTGGATCCTGCTCCCTGTGTCCCTGGCACCTTCCACCCCGCCC CGTCTCTCCTGGATCCTGCTCCCTGTGTCCCTGACTGGCTGTGCCCTGACCCAGGCTCCT GTGACCTCCTCTCTCCCCCATCCCAGCGGCTCTGGGCTCACTGCCAGGTGCCCCACTTCT CCTGGTTCCTTGTGGTTTCCCGCCCTGTGTCCAATGCCTGCCTGGTGCCACCGGAGGGGA CACTGCTGTGCTCCTCGGGTCATCCTGGGGTCAAAGTCATCTTCCCCCCTGGGGCCACTG AGGAGCCTCGTCGAGTCTCCATGCAGGTATGGCCAGGACAGCACTGAGGGTGGCAGGCCG CGCCTCAGCCCACAGGCAGGTGCTCAGGGGGCCTGTCTGCCCCAGGTGGTGCGCATGGCT GGCCGAGAGCTGCAGGCCCTCCTGGGAGAACCAGAGGCTGCAGTGAGCCCCCTGCTGTGC CTGTCACAGAGCGGTCCCCCCAGCTTCCTCCAACCGGTCACCGTGCAGCTGCCTCTGCCC TCTGGCATCACAGGTGAGAGGCAGCCATGGGGCATACCTGGACCTGTGGCCATAGGGTGG AGGGGGTCTCCGGCCAGGAGGCCTCAGCTCGCTGCCCCTCCCATCCCCAGGCCTCAGTCT GGACCGCTCCCGCCTGCACCTGTTGTACTGGGCCCCTCCTGCAGCCACCTGGGATGACAT CACAGCTCAGGTGGTCCTGGAGCTCACCCACCTGTACGCACGCTTCCAGGTCACACACTT CTCCTGGTCAGTGCCCCCCAGCTTTCTCAGCCCCCCTCCCCCAGTCTGTACAGCCCTCCT CACCCCCAGCTCTCCCAGGTACTGGCTCTGGTACACCACCAAGAACTGTGTGGGAGGCCT GGCTCGGAAGGCCTGGGAGCGGCTGCGGCTGCACCGTGTGAACCTCATCGCTCTGCAGCG GCGCCGGGACCCTGAGCAGGTCCTGCTGCAGTGCCTGCCCCGAAACAAGGTGGGGGCACG GGCCGGAGGGCAGCAGGGTGGTGACCAGAGGGCTGGGGTGGGGTGCAGAGCTTTGGGTCC TGAGCTGCACGGGCTTCCCCGCAGGTGGACGCCACCCTTCGGCGGCTGCTGGAGCGGTAC CGGGGCCCCGAGCCCTCTGACACGGTGGAGATGTTCGAGGGCGAAGAGTTCTTTGCGGCC TTCGAGCGCGGCATCGACGTGGATGCTGGTAGGGATGCTGGTGGATGCTCCCTGCCCTGG AGGGGGAGCCTTACCGTCCTCCCCGAGCCCTCCTTGCTCAGCCCACCCCTGTCCCCTAGA CCGCCCTGACTGTGTGGAGGGCAGAATCTGCTTTGTCTTCTACTCGCACCTGAAGAATGT GAAGGAGGTATACGTGACCACCACTCTGGACCGGGAGGCTCAGGCTGTGCGGGGCCAGGT GGGCGAGGGGAGTGGGTGAGGGGAGAGGCCCCCCAGGCCGCTTGGGCAGAGGACCGAACT CCGAACCCCATTCGATGCCCCTTCAGGTGTCCTTCTACCGTGGCGCGGTGCCTGTGCGGG TGCCCGAGGAGGCTGAGGCTGCCCGGCAGAGGAAGGGCGCAGACGCCCTGTGGATGGCCA CTCTGCCCATCAAGCTGCCGGTGGGACTGAGGGACAGCAGAGGGGCGGGGCAGGACCGAG GCCCAGGGGTGACCAGGGTGACATGGTGGAGTTGGGGGTGGAGCCCAGGGCTTAATGCAC TTTTTCCTTCCAACAGAGACTTCGAGGGTCCGAGGGGCCACGGCGGGGGGCTGGCCTCTC CTTGGCACCCTTGAATCTGGGAGATGCCGAGACCGGCTTTCTGACGCAGAGCAACCTGCT GAGTGTGGCTGGGCGTCTGGGTCTGGACTGGCCAGCCGTGGCCCTGCACCTGGGGGTGTC CTACCGGGAGGTGCAGCGCATCCGGCACGAGTTCCGGTGAGGCTCCCACTGCCCGCTGGC TGCCAGCCCCAGGGCTGAGCCCTGGCTGCCTGGAGGGCCCACCTGATTCTGACAGAAGTT TCTTCCAGGGGAGGTGGGGGAAGGGCAAACACCAGGCTGGAAAGGAAAGGTCTGGCCGCA CCTGGCCCCAGGAGCCGGGAACTCCCCCACACTCCGAGGCAGAGTGTGGTGGGGGGTCCT GGGCAGGTGGACAGGACCCCTCTGTCGCCCATCCTCTGCCTGCAGGGATGATCTGGATGA GCAGATCCGTCACATGCTCTTCTCCTGGGCTGAGCGCCAGGCTGGGCAGCCAGGGGCTGT GGGGCTCCTGGTGCAGGCCCTGGAGCAGAGTGACCGGCAGGACGTGGCTGAAGAGGTGCG CGCAGTCTTGGAGCTCGGCCGCCGCAAGTACCAGGACAGCATCCGACGCATGGGCTTGGC CCCCAAGGACCCCGCTCTGCCTGGCTCCTCGGCTCCACAGCCCCCAGAGCCTGCCCAGGC CTAGGCCCCACAGACTTTTAGGCTGGCCCAGATATTCCCCAGTGGATGGGCAGAGCCCCC ACCTTCAAGTCTCTCCAGTGTGTGGGGACGGGTCCCTGTGAGCAACAAAACTGCACTGTT TCTTTCACCTCA OMIM ID 605247