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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPY (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5539 Official gene symbol PPY Full name pancreatic polypeptide Aliases ,PNP, Gene summary This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. [provided by RefSeq] Location Chromosome: 17   Locus: 17q21 Gene position 42019833 - 42018172  Map Viewer Gene orientation minus Gene size 1662 bp Gene sequence >PPY:complement(7292324..7293985):Length=1662 GGCAGGTGCTCGCTTGGTCTAGTGCCCATTTACTCTGGACTCCGGGTAAGTGGGCTCAGC CTGCCTGGGGCTCTGGGGGCCTCCCCCAGGCTGGGGCCTGGGATGGAGAGGAGGTGGTGC TTTGCAGGGCCAGGGGCCTTGGGAGGCCTAAGGTCCTGCTTGGGTCTTGCTTTCTGCATC TGGACAGACCTGTCACGCTAGAAGAGCCGTCTGCTGACTGCACGTGTGTGTGCACACTCG TGTGCATGGCTGTGAACTGGAATGTGTGACTGTGACCTTGTGAGTGACTGGGGTCCCTGT GTGAGTGCCTTTGCTGGTCTGTGCAGGACGACATGGACAGTAGCGTCTTCTCCAGGACCG ATATCTGTGTCTCTATCGCAGGGTGGAGGGCCAGACCCACAAGGCCATGGATTTCTGTCC TTGGCTTCCCGAGTTCATTCTGTGTCCCCCACCCTGTGGGTGACCTGGCATGCCCTTATT CCCACTAGCTGCTGCCTCCTGGGAGCCATGAGGCCCTGGATGTCATGAGTCCCGTGTCTC CAGGACTCACATCCCCATTTTCTCTGCTATACTTTTCTAACTTGCGAGGCCCTGGCTTGC TGGGCTGCTCACAGGACAGGCTGTCCGTGCCTTCAGAGCAGTGTCTAGGAGGTGGAGTGG CCAGCTTGGAGTGGCCCTTTGCTCTGCCCCCTTGTCCCCAGGCTTGGAGAAATGGATGAT GGGCTAAGGGGCTGGATAGTTGGGCCCTGCTTCCTGGGCACGGGAAAATCTGCAGCCCGG GCTCTCCACCTCCCCTCTGCTTGCTCCTCAGATGGCTGCCGCACGCCTCTGCCTCTCCCT GCTGCTCCTGTCCACCTGCGTGGCTCTGTTACTACAGCCACTGCTGGGTGCCCAGGGAGC CCCACTGGAGCCAGTGTACCCAGGGGACAATGCCACACCAGAGCAGATGGCCCAGTATGC AGCTGATCTCCGTAGATACATCAACATGCTGACCAGGCCTAGGTGTGTGCCACAGTTGGG GAGAGAGATCCCAGCCCCTGGGACCCTGGGCCCACTCCACATTCCTGGCCACACCCTATC CCCAGCCCCAGCCCCAGCCCCTTCCAGGCCTGCTCTTGGGAAAACAGGGCATCTGTGCTC AACAGGCCTAGACCAATGTGCCCTGGGCAAGATGGTGCCTACAGGCAGATATGAAACAGG TGGGCTGGCACCTGGGCACAGTGCTTGCCCCTGCTGCCTCTTCCCTCCCAGGTATGGGAA AAGACACAAAGAGGACACGCTGGCCTTCTCGGAGTGGGGGTCCCCGCATGCTGCTGTCCC CAGGTGAGTTTGACTCCCTGCCCTGTCTGTCCAGCTCCCTGGAGCTGAAATGGGGGTGGT GGGACTGAATCAGGGCTTGGAAAGGTGTAGTGGGGGGTGGAAGAGGGAGAACAGGAGCCC AGGGCCAGCCTGAGGCCTCCTGAGGGCACGAGGCCTACCCCCTACACTGCCATGTTCTGC CCTGTCCTCACAGGGAGCTCAGCCCGCTGGACTTATAATGCCACCTTCTGTCTCCTACGA CTCCATGAGCAGCGCCAGCCCAGCTCTCCCCTCTGCACCCTTGGCTCTGGCCAAAGCTTG CTCCCTGCTCCCACACAGGCTCAATAAAGCAAGTCAAAGCCA OMIM ID 167780