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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SRGN (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5552
Official gene symbolSRGN
Full nameserglycin
Aliases,FLJ12930,MGC9289,PPG,PRG,PRG1,
Gene summaryThis gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q22.1
Gene position70847828 - 70864567  Map Viewer
Gene orientationplus
Gene size16740 bp
Gene sequence
OMIM ID177040