| Entrez gene ID | | 5553 |
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| Official gene symbol | | PRG2 |
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| Full name | | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
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| Aliases | | ,BMPG,MBP,MBP1,MGC14537, |
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| Gene summary | | The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. [provided by RefSeq] |
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| Location | | Chromosome: 11 Locus: 11q12 |
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| Gene position | | 57158130 - 57154834 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 3297 bp |
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| Gene sequence |
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| OMIM ID | | 605601 |
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