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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STAB2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID55576
Official gene symbolSTAB2
Full namestabilin 2
Aliases,DKFZp434E0321,FEEL2,FELE-2,FELL2,FEX2,HARE,
Gene summaryThis gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q23.3
Gene position103981069 - 104160502  Map Viewer
Gene orientationplus
Gene size179434 bp
Gene sequence
OMIM ID608561