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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for OTUB1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID55611
Official gene symbolOTUB1
Full nameOTU domain, ubiquitin aldehyde binding 1
Aliases,FLJ20113,FLJ40710,HSPC263,MGC111158,MGC4584,OTB1,OTU1,
Gene summaryThe product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13.1
Gene position63753325 - 63765892  Map Viewer
Gene orientationplus
Gene size12568 bp
Gene sequence
OMIM ID608337