Entrez gene ID | | 55617 |
Official gene symbol | | TASP1 |
Full name | | taspase, threonine aspartase, 1 |
Aliases | | ,C20orf13,FLJ20212,MGC39159,dJ585I14.2, |
Gene summary | | This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20p12.1 |
Gene position | | 13619583 - 13370036 Map Viewer |
Gene orientation | | minus |
Gene size | | 249548 bp |
Gene sequence |
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OMIM ID | | 608270 |
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