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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PRKAA1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5562
Official gene symbolPRKAA1
Full nameprotein kinase, AMP-activated, alpha 1 catalytic subunit
Aliases,AMPK,AMPKa1,MGC33776,MGC57364,
Gene summaryThe protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
LocationChromosome: 5   Locus: 5p12
Gene position40798297 - 40759481  Map Viewer
Gene orientationminus
Gene size38817 bp
Gene sequence
OMIM ID602739