Entrez gene ID | | 5562 |
Official gene symbol | | PRKAA1 |
Full name | | protein kinase, AMP-activated, alpha 1 catalytic subunit |
Aliases | | ,AMPK,AMPKa1,MGC33776,MGC57364, |
Gene summary | | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5p12 |
Gene position | | 40798297 - 40759481 Map Viewer |
Gene orientation | | minus |
Gene size | | 38817 bp |
Gene sequence |
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OMIM ID | | 602739 |