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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for VAC14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID55697
Official gene symbolVAC14
Full nameVac14 homolog (S. cerevisiae)
Aliases,ArPIKfyve,FLJ10305,FLJ36622,FLJ46582,MGC149815,MGC149816,TAX1BP2,TRX,
Gene summaryThe content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM]
LocationChromosome: 16   Locus: 16q22.1-q22.2
Gene position70835061 - 70721342  Map Viewer
Gene orientationminus
Gene size113720 bp
Gene sequence
OMIM ID604632