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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for VPS35 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID55737
Official gene symbolVPS35
Full namevacuolar protein sorting 35 homolog (S. cerevisiae)
Aliases,DKFZp434E1211,DKFZp434P1672,FLJ10752,FLJ13588,FLJ20388,MEM3,
Gene summaryThis gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q12
Gene position46723144 - 46693589  Map Viewer
Gene orientationminus
Gene size29556 bp
Gene sequence
OMIM ID601501