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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NUP133 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID55746
Official gene symbolNUP133
Full namenucleoporin 133kDa
Aliases,FLJ10814,MGC21133,hNUP133,
Gene summaryThe nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q42.13
Gene position229644088 - 229577044  Map Viewer
Gene orientationminus
Gene size67045 bp
Gene sequence
OMIM ID607613