| Entrez gene ID | | 5588 |
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| Official gene symbol | | PRKCQ |
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| Full name | | protein kinase C, theta |
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| Aliases | | ,MGC126514,MGC141919,PRKCT,nPKC-theta, |
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| Gene summary | | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq] |
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| Location | | Chromosome: 10 Locus: 10p15 |
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| Gene position | | 6557111 - 6469105 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 88007 bp |
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| Gene sequence |
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| OMIM ID | | 600448 |
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