Entrez gene ID | | 55907 |
Official gene symbol | | CMAS |
Full name | | cytidine monophosphate N-acetylneuraminic acid synthetase |
Aliases | | ,-, |
Gene summary | | The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12p12.1 |
Gene position | | 22199159 - 22218602 Map Viewer |
Gene orientation | | plus |
Gene size | | 19444 bp |
Gene sequence |
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