Entrez gene ID | | 55914 |
Official gene symbol | | ERBB2IP |
Full name | | erbb2 interacting protein |
Aliases | | ,ERBIN,LAP2, |
Gene summary | | This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q12.3 |
Gene position | | 65222384 - 65376850 Map Viewer |
Gene orientation | | plus |
Gene size | | 154467 bp |
Gene sequence |
| |
OMIM ID | | 606944 |
|