| Entrez gene ID | | 55929 |
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| Official gene symbol | | DMAP1 |
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| Full name | | DNA methyltransferase 1 associated protein 1 |
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| Aliases | | ,DKFZp686L09142,DNMAP1,DNMTAP1,EAF2,FLJ11543,KIAA1425,MEAF2,SWC4, |
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| Gene summary | | This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq] |
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| Location | | Chromosome: 1 Locus: 1p34 |
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| Gene position | | 44679125 - 44686351 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 7227 bp |
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| Gene sequence |
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| OMIM ID | | 605077 |
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