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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAPK1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5594
Official gene symbolMAPK1
Full namemitogen-activated protein kinase 1
Aliases,ERK,ERK2,ERT1,MAPK2,P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk,
Gene summaryThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.2|22q11.21
Gene position22221970 - 22113946  Map Viewer
Gene orientationminus
Gene size108025 bp
Gene sequence
OMIM ID176948