Entrez gene ID | | 55959 |
Official gene symbol | | SULF2 |
Full name | | sulfatase 2 |
Aliases | | ,DKFZp313E091,FLJ44488,FLJ90554,HSULF-2,KIAA1247,MGC126411, |
Gene summary | | Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM] |
Location | | Chromosome: 20 Locus: 20q12-q13.2 |
Gene position | | 46415360 - 46286150 Map Viewer |
Gene orientation | | minus |
Gene size | | 129211 bp |
Gene sequence |
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OMIM ID | | 610013 |
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