Entrez gene ID | | 55997 |
Official gene symbol | | CFC1 |
Full name | | cripto, FRL-1, cryptic family 1 |
Aliases | | ,CRYPTIC,FLJ77897,HTX2,MGC133213, |
Gene summary | | This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. These proteins play key roles in intercellular signaling pathways during vertebrate embryogenesis. Mutations in this gene can cause autosomal visceral heterotaxy. This protein is involved in left-right asymmetric morphogenesis during organ development. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q21.1 |
Gene position | | 131357082 - 131350335 Map Viewer |
Gene orientation | | minus |
Gene size | | 6748 bp |
Gene sequence |
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OMIM ID | | 605194 |
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