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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAPK11 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5600 Official gene symbol MAPK11 Full name mitogen-activated protein kinase 11 Aliases ,P38B,P38BETA2,PRKM11,SAPK2,SAPK2B,p38-2,p38Beta, Gene summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. [provided by RefSeq] Location Chromosome: 22   Locus: 22q13.33 Gene position 50708779 - 50702142  Map Viewer Gene orientation minus Gene size 6638 bp Gene sequence >MAPK11:complement(287365..294002):Length=6638 TCGGGCGCGGGCGCGGGGCGCGGGGCTGGGCCCGGGCGGAGCGGCGGCTGCTCCGGACAT GTCGGGCCCTCGCGCCGGCTTCTACCGGCAGGAGCTGAACAAGACCGTGTGGGAGGTGCC GCAGCGGCTGCAGGGGCTGCGCCCGGTGGGCTCCGGCGCCTACGGCTCCGTCTGGTAGGG GCGGGGCAGAAGGGGTGCTGGGTGGGGGCCGGGCCGGGCCGGAGAGCGCGTCCCCTCCTC GCCCGCGCGAGGTTCTCGGCGTGGGGAGGGGCCTCGCCCTGCCTCCGCCCCCGGGCGCCA AGCGGATCTGAGGAATGAATGGGGGGGCGGGGGTGGCGGCGTAAAGAAACTTTCCAAGCA GACGCCGTTACCGGGAGGGAGGGGGGTCCTCCGGCCTCTCCCGATTCGGACTGCTCCCCA CCAGGCCTGAGGCCTGGGAGGTCACAGCTGGCGTGAGGGTGGGTCTCACGCGACCGAGCC CCGAGCCACCCTGATGTCCGGGCCCCTAAACGTCTGAGCACCCACCTGAGATTCACTGAG TCGGGTCAGGCAGCCCCCCGGGGTCTAGCGGATGACCCTCCCCCGCCCGGGCTGGGGGCT ATTGTCTGAAAAGGGAAGCCCCGCTCCCGGAAGCCAAGATCTCTCCCCCTGGGATGGCCT CAGACTCCCCCTCAGACCACAAACCCCACTTAGGCCCTGGGGCCAGAGGACCTGGCCTGG GGCCCAGGAAGACGACAGAGTCTGGGTGGGGGAGGGGGGTCAACTGGGCCAAGGTCTCTG TTAGACCCGGGTAGCCAGGGCTGGAGGGGCTTAGGGTGAGGTAGTTACCGGGAGTCCTAA GTTTCAGCCTCCATGTTGACTGGGAGGCTGATCATGGGTACAGGCTTTGAGAGGTGCAGC TGAGTCCTCACCATGGCCAATGCCGCTTAGCTGCTGCCCACTGGGGGGTCCTGGTGGGGC GCAAAGGCAGAGGCAGCCAGGGCAGAGCTCTGCCCCAGGCACTTGCAGGTTGGAAGTGGG ACCTCTAGGCCCACCAGATTTGGAGCTCAGGAGCCGGCATCAGGGGCCGGGGGTCCCAGG GCAGGCTGTCTTCTGGTGTGGTCCCTAGCCTTCCATCAGAAGCTGTAGGTGGGTCATTCT AGCCATCATGCCAGCACAGATCTGTCTTCCTCTTTGAGACCTGAAGGGCAGGAAGAGGGT CTGGGACGGTGTGGGAGTGGCCATAGGGGACTAGGGTGGGTCATGGCTGGACTCGCCGTC TGGGAGTTGCTGAGAGGTGTCCGGTTCTCTGAGTGAGGCCTGGTCTCCCCCCTTGCACCC CTGGCCCATTTTCTTAGTTCCACTGCCAAGGCTGCGGGCCAGGTGCCAATTCCCTGTCAC CTGACCGCACAGATGCAATTGGCCAAAAGAACTTGCTGCCCCACGTGCAGGGCCACTCCC CTCACCACCTCAGGAGCACCTTTCCCTGGTCATAGGCTGGGAGCATGGCTGCCCCAGGCA CCTCGACCTGCGCCCATGAGCATCCCAGACCCAGCAGGAGCCGCTCCTGCTCCCCTTGTG TGGGCATGGGGGGTGGCCTCAGCCTCCACTTGCTCTGAGACAGGATCCCAAGAGACAGAA GTGGGAGGGAGAGAAGAAGCAAGTATCAGCCAGAGGGAACAGGCTGTGCAAAGGCCTTTC CTTTAGCAGGGCTGAGGGCAGTGGGACATGGGAGGGTGGGATGAGGGTCACCTGCAAAGG GAGGGTGGGCTCAGGAAGCTGGTGCAGGGTAGAGGGTCTGGACCTCTGGGAAGTGGGGCT GGGCGAAGGGCTGTTCTGTGGGTCCAGCTGACGCCCTCAGCTGTACATCACCTTCTGTCC CGGTTTTGTTCCAAATAATGATGCAATAAACACCTCTGACCAACTTTCCCTCCGTATTTT GAACATTCGGAGGCACCAGGGGTCCAGGGGCTTTGAGGTGGCTCTAGAATCCCCCTCTGT GAGCCTCCTGGGCCCATGGGGTCTATGGGGCAGAGGGAGGCCCGTCTGCTGCAGGTGAAT GCCAGTGACTGTTTTCCTGCTGTGTTTTTCCACGCTGGATGGGGCACCTCTCCCCCAGCC TTGCTTTGAATGGGGGCCCCTGGTTGAGCGTGGGAATCAGTGGGGCCAGGGGACAGAGAA GGTCCAGGACCTTGTGGGGTGAACACACGCATGGTGGTCCAGCCCCAGGGGCTCCTTCCC AGCAAGCGCGGAGTGGGTAGGCCCGAGGGTGGGAGGCCGAGCTGGGGCGGCGGGGCCGGG GCAGAAAAGCCCCACGGCCCCATCCCCACGGAGAAGCGGCGAGAGGGACGCCGCCCGGGT CCACGCGCGTGCGGCCGCCCTCGGACCCCTCCCGGCGCCGCCTCACTCGCCCGCCTTCCA GTTCGGCCTACGACGCCCGGCTGCGCCAGAAGGTGGCGGTGAAGAAGCTGTCGCGCCCCT TCCAGTCGCTGATCCACGCGCGCAGAACGTACCGGGAGCTGCGGCTGCTCAAGCACCTGA AGCACGAGAACGTGAGCCGGGGGAGGGCCGTGGGGGGAGGGCGCGTGCGGGGGCGGGGCC GCGGCGCAGCCAATAGGCGGGCGAGCCCTGGCGATGGGGGCGGGGACACAGGGGGCGCGG CCTGGCACTGGGGGCGTGGCCCGGGGGGAGCTGAACGACAGCCGGGGGTTCGTCGCCCGG CCCTGACGCCCCCCGCCACCTAGGTCATCGGGCTTCTGGACGTCTTCACGCCGGCCACGT CCATCGAGGACTTCAGCGAAGTGTGAGCGGCGGGGCGGGCGAGGCAGCGGGGAGCGCGTT CGCGGTGGGGCGGTGGGGCCCTGTCCTGACCCCCTGACCCCGCCCCAGGTACTTGGTGAC CACCCTGATGGGCGCCGACCTGAACAACATCGTCAAGTGCCAGGCGCTGAGCGACGAGCA CGTTCAATTCCTGGTTTACCAGCTGCTGCGCGGGCTGAAGGTGGGGCGCCCTGGGCTTCG CGGGTCCTCTCGCAGGGGGGCGGGCGGGCCGGGCCCGGCGCTCACCACAATCCCCCTCCC GCAGTACATCCACTCGGCCGGGATCATCCACCGGGTAGGTGCGACCGCAGGGTGAGGGTC GGGTCCAGCAGGGCTCCGTCCCAGCCTCCTGTGCTCACGCTCCGCGTGACCTGCAGGACC TGAAGCCCAGCAACGTGGCTGTGAACGAGGACTGTGAGCTCAGGGTGAGGCCCGTGGGCA GGGGTGGGCAGGGCGGCGGCGGAGCCCGTGCGGAGCTTGAGAACACCACGTGGTCGCCCC AGATCCTGGATTTTGGGCTGGCGCGCCAGGCGGACGAGGAGATGACCGGCTATGTGGCCA CGCGCTGGTACCGGGCACCTGAGATCATGCTCAACTGGATGCATTACAACCAAACAGGTG CAGGGGGAAGGCCTTGGGGGGACGAAGGCCAAGGGCCTCGTCTGGCCCTCGACTGGCTCT GCATGCCAGGTCTTAGGGGGCAGGCAAGGTCCCCAAGAATGTGGGACCCACATTCAAAAG TAGCCCTTCAGAGGCCGCTAGAGCATGATGGGTGCTGGCCTCCTCTGGCTGTGCAGCTAT GGACCTCCCCCTGCCTAGGGGGGTTGGGTATGGCAGAGGAGGGGGTCTGCCCATCTTGGG GTCTGGATGTGACTGTGGGTCTCCTGGAGGAGGGACGTGGGGTGGGCACACTGATGGAGG TCCCCTCGCCCTCGCACAGTGGATATCTGGTCCGTGGGCTGCATCATGGCTGAGCTGCTC CAGGGCAAGGCCCTCTTCCCGGGAAGCGACTGTATCCTTGGCCCAGGTTGGGGAGCAGGG TCAAACAGGGCCCCTCCTGTAGGGTAGGGACCAGCGCTGGCCCCTTCTGGCGGGTCTTGC CTCCTCTGCCCCCCATGCTATGCTACTTTGGGCTGGCCATCCTCACCTATAGGAGAGCGG GCTCTGGGCAGCGCCCCAAAGTTTTGGGTCTGGGGGCCCAGGAGGGGTCTGTGGCTGGCC CGTGGGTGTTTCCTGAGTGACACAGACATTGACCAGCTGAAGCGCATCATGGAAGTGGTG GGCACACCCAGCCCTGAGGTTCTGGCAAAAATCTCCTCAGAACACGTGAGTTGGTGCCCG CCAGCCAGCAGCTCCCTCTCCTGGCTGAGCCCCCAGGCTCTCTGGGGGAGAGGGTGGTGT GGAAATGCGGGGACCATATGGGGAACATGGGATGTGGTGGGATAGAGCCTAGGGCAGGTG CCCAATCCCTGCAGGGGAAACAGGAGAAGGGGGAAGACATTCCTGACACCAGGGACAGTG AGTGCAAAGCCATGACCCCAGCAAGCAGTGCCTGGCCAGGGCAGTGGGGGTGGGCTGGGG GCCCAGCAAGCAGTGCCTGGCCAGGGCAGTGGGGGTGGGCTGGGGGACCCCAGCAAGCAG TGCCTGGCCAGGGCAGTGGGGGTGGGCTGGGTGGAGGGAGTGTACTTGGACCCAGCTCCT GCAGGCATTAGGGGCCAACTGAGGAGCTAGAACCACCAGATCCTATATGGAGGGGGTCAC TGGTCTGCCTGTGCCCTTGTCCTGGCCTGTTGGAGTGAATGAGTCTGGGGGCTTGCCAAG AGAAGCCCCAGTTTGGGGCCAGGGAGGCAGAGAGTGAGCAGCCTCCCCAGGTGTTCTTGT GTGCCCCCAGGCCCGGACATATATCCAGTCCCTGCCCCCCATGCCCCAGAAGGACCTGAG CAGCATCTTCCGTGGAGCCAACCCCCTGGGTGAGGACTGCCCTGGGCTAGACTGGGCTCC ATATCTGGCCCTGGATGTACAGCTGACCCCCCTCCCCACCACTGGCTTCCCTGCAGCCAT AGACCTCCTTGGAAGGATGCTGGTGCTGGACAGTGACCAGAGGGTCAGTGCAGCTGAGGC ACTGGCCCACGCCTACTTCAGCCAGTACCACGACCCCGAGGATGAGCCAGAGGCCGAGCC ATATGATGAGAGCGTTGAGGCCAAGGAGCGCACGCTGGAGGAGTGGAAGGGTGAGCATGG CAGTGGCTGGGGGTGGGTCCAGGGGCCTGCGGGCTCCATTTCCCCAGAGGCAGGAAATGC CCCAGTTCCTCTCCAGACTGGTCAGGTGTGGAAGGGCGTTCAGGTGTCCAGCACAGGCTG GGAGCGGGGCGGAGGAGTGACACAGGGCAGGTTCTGGCTCCCAGACTGTGCTGAGGCTGC TGTCACAGGGTGGTGGGCCTGGGCTGGGTGGCAGGTGCCAGACAAGCAGGTGAGGGGCCG GGCTGTGGGAGGCACAAGCTCACCCTTTCCCTTCACCTCCTAGAGCTCACTTACCAGGAA GTCCTCAGCTTCAAGCCCCCAGAGCCACCGAAGCCACCTGGCAGCCTGGAGATTGAGCAG TGAGGTGCTGCCCAGCAGCCCCTGAGAGCCTGTGGAGGGGCTTGGGCCTGCACCCTTCCA CAGCTGGCCTGGTTTCCTCGAGAGGCACCTCCCACACTCCTATGGTCACAGACTTCTGGC CTAGGACCCCTCGCCTTCAGGAGAATCTACACGCATGTATGCATGCACAAACATGTGTGT ACATGTGCTTGCCATGTGTAGGAGTCTGGGCACAAGTGTCCCTGGGCCTACCTTGGTCCT CCTGTCCTCTTCTGGCTACTGCACTCTCCACTGGGACCTGACTGTGGGGTCCTAGATGCC AAAGGGGTTCCCCTGCGGAGTTCCCCTGTCTGTCCCAGGCCGACCCAAGGGAGTGTCAGC CTTGGGCTCTCTTCTGTCCCAGGGCTTTCTGGAGGACGCGCTGGGGCCGGGACCCCGGGA GACTCAAAGGGAGAGGTCTCAGTGGTTAGAGCTGCTCAGCCTGGAGGTAGGGGGCTGTCT TGGTCACTGCTGAGACCCACAGGTCTAAGAGGAGAGGCAGAGCCAGTGTGCCACCAGGCT GGGCAGGGACAACCACCAGGTGTCAAATGAGAAAAGCTGCCTGGAGTCTTGTGTTCACCC GTGGGTGTGTGTGGGCACGTGTGGATGAGCGTGCACTCCCCGTGTTCATATGTCAGGGCA CATGTGATGTGGTGCGTGTGAATCTGTGGGCGCCCAAGGCCAGCAGCCATATCTGGCAAG AAGCTGGAGCCGGGGTGGGTGTGCTGTTGCCTTCCCTCTCCTCGGTTCCTGATGCCTTGA GGGGTGTTTCAGACTGGCGGCTCCAGTGGGCCAAAGGGCAACCACATGAGCATGGGCAGG GGCTTTCTCCTTGGATGTGGGACCCACAGCAGCTTCCTGAGGCTGGGGGTGGGTGGGTGG GTGGTTTGGCCTTGAGGACGCTAGGGCAGGCAGCACACCTGGATGTGGACTTGGACTCGG ACACTTCTGCCCTGCACCCTGGCCCGCTCTCTACCTCTGCCCACCGTTGTGGCCCTGCAG CCGGAGATCTGAGGTGCTCTGGTCTGTGGGTCAGTCCTCTTTCCTTGTCCCAGGATGGAG CTGATCCAGTAACCTCGGAGACGGGACCCTGCCCAGAGCTGAGTTGGGGGTGTGGCTCTG CCCTGGAAAGGGGGTGACCTCTTGCCTCGAGGGGCCCAGGGAAGCCTGGGTGTCAAGTGC CTGCACCAGGGGTGCACAATAAAGGGGGTTCTCTCTCA OMIM ID 602898