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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAP2K1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5604
Official gene symbolMAP2K1
Full namemitogen-activated protein kinase kinase 1
Aliases,MAPKK1,MEK1,MKK1,PRKMK1,
Gene summaryThe protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q22.1-q22.33
Gene position66679211 - 66783882  Map Viewer
Gene orientationplus
Gene size104672 bp
Gene sequence
OMIM ID176872