Entrez gene ID | | 56172 |
Official gene symbol | | ANKH |
Full name | | ankylosis, progressive homolog (mouse) |
Aliases | | ,ANK,CCAL2,CMDJ,CPPDD,FLJ27166,HANK,MANK, |
Gene summary | | This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5p15.1 |
Gene position | | 14871887 - 14704909 Map Viewer |
Gene orientation | | minus |
Gene size | | 166979 bp |
Gene sequence |
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OMIM ID | | 605145 |