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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PROS1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5627
Official gene symbolPROS1
Full nameprotein S (alpha)
Aliases,PROS,PS21,PS22,PS23,PS24,PS25,PSA,
Gene summaryThis gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q11.2
Gene position93692934 - 93591881  Map Viewer
Gene orientationminus
Gene size101054 bp
Gene sequence
OMIM ID176880