Entrez gene ID | | 5627 |
Official gene symbol | | PROS1 |
Full name | | protein S (alpha) |
Aliases | | ,PROS,PS21,PS22,PS23,PS24,PS25,PSA, |
Gene summary | | This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q11.2 |
Gene position | | 93692934 - 93591881 Map Viewer |
Gene orientation | | minus |
Gene size | | 101054 bp |
Gene sequence |
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OMIM ID | | 176880 |
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