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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RELN (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5649
Official gene symbolRELN
Full namereelin
Aliases,PRO1598,RL,
Gene summaryThis gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q22
Gene position103629963 - 103112231  Map Viewer
Gene orientationminus
Gene size517733 bp
Gene sequence
OMIM ID600514